Jia Ju, Yuan Lin, Gao Wei, Yao Kai-Hu
National Center for Children's Health/Beijing Children's Hospital, Capital Medical University/Beijing Pediatric Research Institute/Key Laboratory of Major Diseases in Children, Ministry of Education, Beijing 100045, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2019 Jul;21(7):713-717. doi: 10.7499/j.issn.1008-8830.2019.07.018.
Patients with pertussis can have a variety of complications, including pneumonia and subconjunctival hemorrhage. Severe complications, such as pulmonary hypertension and encephalopathy, can be life-threatening. Younger children with pertussis may lack the characteristic clinical manifestations of pertussis, and therefore, a deeper understanding of the complications of pertussis may help to improve the diagnosis, treatment, and prognosis of pertussis. However, there is still no standard for the diagnosis and treatment of pertussis complications, and there are great differences in diagnostic name, basis, and data used in different reports. This article reviews the complications of pertussis which have been reported so far, such as pulmonary complications (pneumonia, pulmonary hypertension, pneumothorax, and mediastinal or subcutaneous emphysema), fractures, hernias, circulatory system complications, nervous system complications (convulsion, encephalopathy, hemorrhage, and hematoma), urinary system complications, and secondary infections, so as to provide a reference for the clinical diagnosis and treatment of pertussis complications, scientific research on pertussis complications, and the promotion of standardized diagnosis and treatment of pertussis complications.
百日咳患者可能会出现多种并发症,包括肺炎和结膜下出血。严重的并发症,如肺动脉高压和脑病,可能会危及生命。患有百日咳的年幼儿童可能缺乏百日咳的典型临床表现,因此,深入了解百日咳的并发症可能有助于改善百日咳的诊断、治疗和预后。然而,百日咳并发症的诊断和治疗仍没有标准,不同报告中的诊断名称、依据和使用的数据存在很大差异。本文综述了迄今为止已报道的百日咳并发症,如肺部并发症(肺炎、肺动脉高压、气胸以及纵隔或皮下气肿)、骨折、疝气、循环系统并发症、神经系统并发症(惊厥、脑病、出血和血肿)、泌尿系统并发症以及继发感染,以便为百日咳并发症的临床诊断和治疗、百日咳并发症的科研以及促进百日咳并发症的规范化诊断和治疗提供参考。