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骨肿瘤的多模态成像方法——最新进展

Multi-modality imaging approach to bone tumors - State-of-the art.

作者信息

Goyal Nidhi, Kalra Manas, Soni Aditi, Baweja Pankaj, Ghonghe Nitin P

机构信息

Indraprastha Apollo Hospital.

出版信息

J Clin Orthop Trauma. 2019 Jul-Aug;10(4):687-701. doi: 10.1016/j.jcot.2019.05.022. Epub 2019 May 31.

Abstract

The approach to the radiographic diagnosis of bone tumors is much beyond the conventional radiographs in present era of multiplanar and functional imaging. Radiographs is still the most pertinent part of initial diagnosis of bone tumors, however, there are few limitations, like lesions in complex anatomy, marrow assessment, soft tissue resolution, which are important for staging. Diagnosis is just one aspect of the tumor evaluation, extent of marrow involvement by the tumor growth, involvement of overlying soft tissue, involvement of adjacent joint, and knowledge about skip lesions and metastasis are equally important for staging and treatment of the disease. Multimodality imaging like CT, MRI helps cover all these aspects. Emerging role of PETCT/PET MRI has further revolutionized the imaging of bone tumors by providing anatomical and morphological characteristics simultaneously and combining the whole body scan in same sitting. This article will discuss the role of various imaging modalities along with illustrative examples of few cases. Team work between radiologist with orthopedic oncologist and pathologist will help in deciding a road map for diagnosing and treatment of bone tumors. Follow up scanning with MRI and PET FDG scan has also been well established in assessing therapeutic response.

摘要

在当今多平面和功能成像的时代,骨肿瘤的放射学诊断方法远不止传统的X线片。X线片仍是骨肿瘤初步诊断中最相关的部分,然而,它存在一些局限性,如复杂解剖结构中的病变、骨髓评估、软组织分辨率等,而这些对于分期很重要。诊断只是肿瘤评估的一个方面,肿瘤生长对骨髓的累及范围、覆盖软组织的累及情况、相邻关节的累及情况以及对跳跃性病变和转移的了解,对于疾病的分期和治疗同样重要。CT、MRI等多模态成像有助于涵盖所有这些方面。PETCT/PET MRI的新兴作用通过同时提供解剖和形态特征并在同一次检查中进行全身扫描,进一步彻底改变了骨肿瘤的成像。本文将讨论各种成像模态的作用,并列举一些病例的示例。放射科医生与骨肿瘤学家和病理学家之间的团队合作将有助于确定骨肿瘤诊断和治疗的路线图。MRI和PET FDG扫描的随访也已在评估治疗反应方面得到充分确立。

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