婴儿绞痛与偏头痛和紧张型头痛的关系：一项荟萃分析。

The Relationship between Infant Colic and Migraine as well as Tension-Type Headache: A Meta-Analysis.

机构信息

Second Ward of Department of Neurology, XuZhou Children's Hospital, Xuzhou Medical University, Xuzhou, Jiangsu, China.

出版信息

Pain Res Manag. 2019 Jun 16;2019:8307982. doi: 10.1155/2019/8307982. eCollection 2019.

DOI:10.1155/2019/8307982

PMID:31316683

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6604354/

Abstract

BACKGROUND

Infant colic is a common benign disease during early infancy. Migraine and tension-type headache (TTH) are the most common primary headache forms among pediatric population. Several studies have investigated the incidence of infant colic in patients with migraine and TTH. The meta-analysis was to assess the relationship between infant colic and migraine as well as TTH.

METHODS

PubMed, Web of Science, and Cochrane Library were searched until August 16, 2018, for potential studies. Data were extracted by two independent authors and analyzed using RevMan 5.2 software. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to determine the association between infant colic and migraine as well as TTH, respectively.

RESULTS

A total of 148 studies were found, and 7 studies were finally included. A higher incidence of colic during infancy was revealed in migraine patients than controls (=0.05, OR: 2.51, 95% CI: 1.32-4.77) and TTH subjects (=0.02, OR: 0.33, 95% CI: 0.13-0.86), respectively. And no significances were found between TTHs with controls (=0.51, OR: 1.17, 95% CI: 0.73-1.89).

CONCLUSION

This meta-analysis indicated that migraine was associated with increased incidence of infantile colic history, but TTH incidence was not relevant with the incidence of infantile colic history.

摘要

背景

婴儿腹绞痛是婴儿早期常见的良性疾病。偏头痛和紧张型头痛（TTH）是儿科人群中最常见的原发性头痛形式。几项研究调查了偏头痛和 TTH 患者中婴儿腹绞痛的发生率。本荟萃分析旨在评估婴儿腹绞痛与偏头痛和 TTH 之间的关系。

方法

检索 PubMed、Web of Science 和 Cochrane Library，以获取潜在的研究，截止日期为 2018 年 8 月 16 日。由两位独立作者提取数据，并使用 RevMan 5.2 软件进行分析。计算比值比（ORs）及其 95%置信区间（CIs），以分别确定婴儿腹绞痛与偏头痛和 TTH 之间的关联。

结果

共发现 148 项研究，最终纳入 7 项研究。与对照组相比，偏头痛患者腹绞痛的发生率更高（=0.05，OR：2.51，95%CI：1.32-4.77），与 TTH 患者相比（=0.02，OR：0.33，95%CI：0.13-0.86），TTH 与对照组之间无显著差异（=0.51，OR：1.17，95%CI：0.73-1.89）。