Effah Kofi, Seidl Stefan, Gorges Edith, Akakpo Patrick Kafui
Battor Catholic Hospital, North Tongu District, Volta Region, Ghana.
22459 Hamburg, Frohmestrasse 59, Hamburg, Germany.
Case Rep Obstet Gynecol. 2019 Jun 17;2019:8521834. doi: 10.1155/2019/8521834. eCollection 2019.
Melanotic schwannoma (MS) is a rare nerve sheath tumor with fewer than 200 cases reported. MS has uncertain malignant potential and comprises 1% of all nerve sheath tumors with a predilection for the spinal nerve roots. An even rarer location for this tumor is the vagina. Up to 55% of MSs that contain psammoma bodies are associated with the Carney complex, an autosomal dominant syndrome. Criteria for malignancy in MS are still not well established and long term follow-up of patients is recommended. A 26-year-old woman presented with a bleeding vaginal tumor which was diagnosed as MS following excision. The clinical, histopathological, and immunohistochemical features of this tumor are discussed.
黑色素性神经鞘瘤（MS）是一种罕见的神经鞘瘤，报告病例少于200例。MS的恶性潜能不确定，占所有神经鞘瘤的1%，好发于脊神经根。该肿瘤更罕见的部位是阴道。高达55%含有砂粒体的MS与Carney综合征相关，这是一种常染色体显性综合征。MS的恶性标准仍未明确确立，建议对患者进行长期随访。一名26岁女性因阴道出血性肿瘤就诊，切除后诊断为MS。本文讨论了该肿瘤的临床、组织病理学和免疫组化特征。
