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Changes in lung microbiome do not explain the development of ventilator-associated pneumonia.

作者信息

Bos Lieuwe D J, Kalil Andre C

机构信息

Intensive Care, Infection and Immunity, Amsterdam UMC -Location AMC, Amsterdam, The Netherlands.

Department of Respiratory Medicine, Infection and Immunity, Amsterdam UMC-Location AMC, Amsterdam, The Netherlands.

出版信息

Intensive Care Med. 2019 Aug;45(8):1133-1135. doi: 10.1007/s00134-019-05691-1. Epub 2019 Jul 17.

DOI:10.1007/s00134-019-05691-1
PMID:31317208
Abstract
摘要

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本文引用的文献

1
Identification of respiratory microbiota markers in ventilator-associated pneumonia.鉴定呼吸机相关性肺炎的呼吸微生物群标志物。
Intensive Care Med. 2019 Aug;45(8):1082-1092. doi: 10.1007/s00134-019-05660-8. Epub 2019 Jun 17.
2
M. pneumoniae and C. pneumoniae are no relevant pathogens in critically ill patients with hospital-acquired respiratory tract infections.肺炎支原体和鹦鹉热衣原体并非重症医院获得性呼吸道感染患者的相关病原体。
Infection. 2019 Jun;47(3):471-474. doi: 10.1007/s15010-019-01273-x. Epub 2019 Jan 28.
3
Airway microbiome research: a modern perspective on surveillance cultures?
采用多重 PCR 检测方法对 COVID-19 危重症患者细菌性肺炎的诊断与治疗:意大利某大型医院五个月的经验。
Microbiol Spectr. 2021 Dec 22;9(3):e0069521. doi: 10.1128/Spectrum.00695-21. Epub 2021 Nov 10.
4
Staphylococcus aureus ventilator-associated pneumonia in patients with COVID-19: clinical features and potential inference with lung dysbiosis.金黄色葡萄球菌性呼吸机相关性肺炎在 COVID-19 患者中的临床特征及与肺菌群失调的潜在关联。
Crit Care. 2021 Jun 7;25(1):197. doi: 10.1186/s13054-021-03623-4.
5
Respiratory microbiome in mechanically ventilated patients: a narrative review.机械通气患者的呼吸微生物组:叙述性综述。
Intensive Care Med. 2021 Mar;47(3):292-306. doi: 10.1007/s00134-020-06338-2. Epub 2021 Feb 9.
6
Temporal airway microbiome changes related to ventilator-associated pneumonia in children.与儿童呼吸机相关性肺炎相关的气道微生物群的时间变化
Eur Respir J. 2021 Mar 18;57(3). doi: 10.1183/13993003.01829-2020. Print 2021 Mar.
7
Reconsidering ventilator-associated pneumonia from a new dimension of the lung microbiome.从肺部微生物组的新维度重新考虑呼吸机相关性肺炎。
EBioMedicine. 2020 Oct;60:102995. doi: 10.1016/j.ebiom.2020.102995. Epub 2020 Sep 16.
气道微生物组研究:对监测培养的现代观点?
Ann Transl Med. 2017 Nov;5(22):445. doi: 10.21037/atm.2017.08.05.
4
The dynamics of the pulmonary microbiome during mechanical ventilation in the intensive care unit and the association with occurrence of pneumonia.机械通气期间重症监护病房肺部微生物组的动态变化及其与肺炎发生的关系。
Thorax. 2017 Sep;72(9):803-810. doi: 10.1136/thoraxjnl-2016-209158. Epub 2017 Jan 18.
5
Dysbiosis of upper respiratory tract microbiota in elderly pneumonia patients.老年肺炎患者上呼吸道微生物群失调
ISME J. 2016 Jan;10(1):97-108. doi: 10.1038/ismej.2015.99. Epub 2015 Jul 7.
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Spatial Variation in the Healthy Human Lung Microbiome and the Adapted Island Model of Lung Biogeography.健康人肺部微生物群的空间变异与适应性肺部生物地理学岛屿模型
Ann Am Thorac Soc. 2015 Jun;12(6):821-30. doi: 10.1513/AnnalsATS.201501-029OC.
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Is bacteremic sepsis associated with higher mortality in transplant recipients than in nontransplant patients? A matched case-control propensity-adjusted study.菌血症性败血症是否与移植受者的死亡率高于非移植患者有关?一项匹配病例对照倾向调整研究。
Clin Infect Dis. 2015 Jan 15;60(2):216-22. doi: 10.1093/cid/ciu789. Epub 2014 Oct 9.
8
Ventilator-associated pneumonia is characterized by excessive release of neutrophil proteases in the lung.呼吸机相关性肺炎的特征是肺部中性粒细胞蛋白酶过度释放。
Chest. 2012 Dec;142(6):1425-1432. doi: 10.1378/chest.11-3273.
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Diagnostic importance of pulmonary interleukin-1beta and interleukin-8 in ventilator-associated pneumonia.肺内白细胞介素-1β和白细胞介素-8对呼吸机相关性肺炎的诊断意义。
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