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成人脊柱畸形手术决策评分。第 2 部分:为 40 岁以上成人脊柱畸形患者制定指导治疗方式选择的评分系统的开发和验证。

Adult spinal deformity surgical decision-making score. Part 2: development and validation of a scoring system to guide the selection of treatment modalities for patients above 40 years with adult spinal deformity.

机构信息

Department of Orthopedic Surgery, Osaka Medical College, 2-7, Daigakumachi, Takatsuki-shi, Osaka, 569-8686, Japan.

L'Institut de la Colonne Vertébrale, Bordeaux University Hospital, Bordeaux, France.

出版信息

Eur Spine J. 2020 Jan;29(1):45-53. doi: 10.1007/s00586-019-06068-0. Epub 2019 Jul 17.

Abstract

PURPOSE

We aimed to develop and internally validate a scoring system, the adult spinal deformity surgical decision-making (ASD-SDM) score, to guide the decision-making process for ASD patients aged above 40 years.

METHODS

A multicentre prospective ASD database was retrospectively reviewed. The scoring system was developed using data from a derivation set and was internally validated in a validation set. The performance of the ASD-SDM score for predicting surgical management was assessed using the area under the receiver operating characteristic curve (AUC).

RESULTS

A total of 702 patients were included for analysis in the present study. The scoring system developed based on 562 patients, ranging from 0 to 12 points, included five parameters: leg pain scored by the numerical rating scale; pain and self-image domains in the Scoliosis Research Society-22 score; coronal Cobb angle; and relative spinopelvic alignment. Surgical indication was graded as low (score 0 to 4), moderate (score 5 to 7), and high (score 8 to 12) groups. In the validation set of 140 patients, the AUC for predicting surgical management according to the ASD-SDM score was 0.797 (standard error = 0.037, P < 0.001, 95% confidence interval = 0.714 to 0.861), and in the low, moderate, and high surgical indication groups, 23.7%, 43.5%, and 80.4% of the patients, respectively, were treated surgically.

CONCLUSIONS

The ASD-SDM score demonstrated reliability, with higher scores indicating a higher probability of surgery. This index could aid in the selection of surgery for ASD patients in clinical settings. These slides can be retrieved under Electronic Supplementary Material.

摘要

目的

我们旨在开发并内部验证一种评分系统,即成人脊柱畸形手术决策(ASD-SDM)评分,以指导年龄大于 40 岁的 ASD 患者的决策过程。

方法

回顾性分析多中心前瞻性 ASD 数据库。该评分系统是使用来自推导集的数据开发的,并在验证集中进行了内部验证。使用受试者工作特征曲线下的面积(AUC)评估 ASD-SDM 评分预测手术管理的性能。

结果

本研究共纳入 702 例患者进行分析。基于 562 例患者开发的评分系统,范围为 0 至 12 分,包括五个参数:数字评分量表评估的腿部疼痛;SRS-22 评分的疼痛和自我形象域;冠状 Cobb 角;以及相对脊柱骨盆排列。手术指征分为低(评分 0 至 4)、中(评分 5 至 7)和高(评分 8 至 12)组。在 140 例验证患者中,根据 ASD-SDM 评分预测手术管理的 AUC 为 0.797(标准误差=0.037,P<0.001,95%置信区间=0.714 至 0.861),在低、中、高手术指征组中,分别有 23.7%、43.5%和 80.4%的患者接受了手术治疗。

结论

ASD-SDM 评分具有可靠性,得分越高,手术的可能性越大。该指数可以帮助临床选择 ASD 患者的手术。这些幻灯片可在电子补充材料中检索。

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