人羊膜塞治疗高度近视黄斑孔伴视网膜脱离
A human Amniotic Membrane plug to manage high myopic macular hole associated with retinal detachment.
机构信息
Department of Translational Surgery and Medicine, Ophthalmology, University of Florence, Careggi, Florence, Italy.
出版信息
Acta Ophthalmol. 2020 Mar;98(2):e252-e256. doi: 10.1111/aos.14174. Epub 2019 Jul 18.
OBJECTIVE
To assess the efficacy of the human amniotic membrane (hAM) to treat (HMMH) associated with retinal detachment (RD).
MATERIAL AND METHODS
Ten eyes of 10 patients with recurrent HMMH and RD, who had already undergone one or more pars plana vitrectomy (PPV), underwent a PPV with an hAM plug implanted in the macular hole. The initial five patients enrolled were tamponaded with (SO) while the subsequent five patients with 10% octafluoropropane (C F ). Silicon oil was removed in all five patients 2 months later. No statistical differences were reported between the two groups.
RESULTS
Final retinal reattachment was achieved in all the patients. BCVA improved from 1.73 logMAR to 0.94 logMAR after 6 months. No adverse events were registered during follow-up.
CONCLUSION
An hAM plug is an efficient substrate to manage HMMH associated with RD resulting in encouraging visual acuity recovery.
目的
评估人羊膜（hAM）治疗与视网膜脱离（RD）相关的黄斑裂孔（HMMH）的疗效。
材料和方法
10 例复发性 HMMH 和 RD 患者的 10 只眼已行一次或多次标准经睫状体平坦部玻璃体切除术（PPV），行 PPV 联合黄斑裂孔内植入 hAM 栓。最初的 5 例患者接受（SO）填充，随后的 5 例患者接受 10%八氟丙烷（C F ）填充。所有 5 例患者均于 2 个月后取出硅油。两组间未报告统计学差异。
结果
所有患者最终视网膜均复位。6 个月后 BCVA 从 1.73 logMAR 提高至 0.94 logMAR。随访期间无不良事件发生。
结论
hAM 栓是治疗与 RD 相关的 HMMH 的有效基质，可获得令人鼓舞的视力恢复。
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