Department of Pediatrics, Pudong New Area Peoples' Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China (mainland).
Department of Gynecology and Obstetrics, Pudong New Area Peoples' Hospital Affiliated to Shanghai University of Medicine and Health Sciences, Shanghai, China (mainland).
Med Sci Monit. 2019 Jul 18;25:5336-5342. doi: 10.12659/MSM.914903.
BACKGROUND This study aimed to evaluate superb microvascular imaging (SMI) as an adjunctive imaging method to evaluate mesenteric lymph nodes in children with mesenteric lymphadenitis compared with healthy children. MATERIAL AND METHODS A retrospective study compared children with mesenteric lymphadenitis (n=27) and healthy children (n=30). Lymph node size was determined using grayscale ultrasonography and parameters of lymph node vascularity were compared using color Doppler flow imaging (CDFI) and SMI. The diagnostic performance of ultrasound (US), US combined with SMI, and US combined with CDFI were compared. RESULTS Lymph nodes from children with mesenteric lymphadenitis (n=77) and normal lymph nodes (n=84) were evaluated by SMI, which showed that the least diameter of lymph nodes in cases of mesenteric lymphadenitis was 0.58±0.15 mm and of normal mesenteric lymph nodes was 0.47±0.08 mm (p<0.001). SMI identified 92.6% of abnormal mesenteric lymph nodes while CDFI detected 85.2%. US combined with SMI had the highest sensitivity (81.5%), and specificity (78.9%) compared with US alone (sensitivity, 63.0%; specificity, 64.9%), and compared with US combined with CDFI (sensitivity, 74.1%; specificity, 75.4%). US combined with SMI and US combined with CDFI achieved the same specificity (76.7%), which was higher than that of US alone (66.7%). CONCLUSIONS SMI was superior to color Doppler flow imaging in evaluating the microvasculature in lymphadenopathy in mesenteric lymphadenitis. SMI may be used as an adjunct to grayscale ultrasonography to assist in identifying mesenteric lymphadenopathy in pediatric patients.
本研究旨在评估超级微血管成像（SMI）作为一种辅助成像方法，用于评估肠系膜淋巴结炎患儿与健康儿童的肠系膜淋巴结，与健康儿童相比。
回顾性研究比较了肠系膜淋巴结炎患儿（n=27）和健康儿童（n=30）。使用灰阶超声测量淋巴结大小，并比较彩色多普勒血流成像（CDFI）和 SMI 评估淋巴结血管参数。比较超声（US）、US 联合 SMI 和 US 联合 CDFI 的诊断性能。
肠系膜淋巴结炎患儿（n=77）和正常肠系膜淋巴结（n=84）的淋巴结进行了 SMI 评估，结果显示肠系膜淋巴结炎患儿的淋巴结最小直径为 0.58±0.15mm，正常肠系膜淋巴结为 0.47±0.08mm（p<0.001）。SMI 可识别 92.6%的异常肠系膜淋巴结，而 CDFI 可识别 85.2%。与单独使用 US（敏感性，63.0%；特异性，64.9%）相比，US 联合 SMI 的敏感性（81.5%）和特异性（78.9%）最高，与 US 联合 CDFI（敏感性，74.1%；特异性，75.4%）相比。US 联合 SMI 和 US 联合 CDFI 的特异性相同（76.7%），高于单独使用 US（66.7%）。
SMI 在评估肠系膜淋巴结炎淋巴结病变的微血管方面优于彩色多普勒血流成像。SMI 可作为灰阶超声的辅助手段，用于辅助识别儿科患者的肠系膜淋巴结病变。
