Narang H K
Public Health Laboratory, Newcastle General Hospital, U.K.
Virus Res. 1988 Mar;9(4):293-305. doi: 10.1016/0168-1702(88)90089-5.
The development of scrapie-associated particles and lesions in four regions of the brain was studied in mice over a period of 30 weeks. Characteristic tubulovesicular particles, identical to those previously described, were first found about half way through the incubation period in mice inoculated by four different routes. The particles are found in brains with scrapie and other spongiform encephalopathies; they have never been seen in other conditions, and potentially represent the infectious agent.
在30周的时间里，对小鼠大脑四个区域中瘙痒病相关颗粒和病变的发展情况进行了研究。与先前描述的颗粒相同的特征性管状囊泡颗粒，在通过四种不同途径接种的小鼠潜伏期大约一半时首次被发现。这些颗粒存在于患有瘙痒病和其他海绵状脑病的大脑中；在其他情况下从未见过它们，并且可能代表感染因子。
