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XAP-Lab:用于设计灵活的 X 射线采集协议的软件工具。

XAP-Lab: A software tool for designing flexible X-ray acquisition protocols.

机构信息

Departamento de Bioingeniería e Ingeniería Aeroespacial, Universidad Carlos III de Madrid, Spain; Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.

Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.

出版信息

Comput Methods Programs Biomed. 2019 Aug;177:243-252. doi: 10.1016/j.cmpb.2019.05.013. Epub 2019 May 16.

Abstract

BACKGROUND AND OBJECTIVE

The availability of digital X-ray detectors, together with the development of new robotized hardware and reconstruction algorithms, opens the opportunity to provide 3D capabilities with conventional radiology systems. This would be based on the acquisition of a limited number of projections with non-standard geometrical configurations. The versatility of these techniques is enormous, enabling the introduction of tomography in situations where a CT system is hardly available, such as during surgery or in an ICU, or in which a reduction of radiation dose is key, as in pediatrics. Computer simulations are a valuable tool to explore these possibilities before their actual implementation on real systems. Existing software tools generally simulate only standard acquisition protocols, such as cone-beam with circular trajectory, thus not allowing the users to evaluate more sophisticated projection geometries. The goal of this work is to design a simulation tool that enables the design of acquisition protocols with flexible projection geometries.

METHODS

We present XAP-Lab, a software tool for the design of X-ray acquisition protocols with flexible trajectories. For a given projection geometry, defined through a graphical user interface, it allows the user to simulate projections using GPU-accelerated kernels, the visualization of the scanned field of view and the estimation of the total radiation dose. The complete acquisition protocol can then be exported with the appropriate format for its use on real systems. We tested the software by optimizing a tomosynthesis protocol and validating the results with real acquisitions using a SEDECAL NOVA FA radiography system and phantoms for quantitative and qualitative evaluation.

RESULTS

Quantitative evaluation using a phantom showed a mean error under 4 mm for each position, below the ±5 mm tolerance of the system specified by the manufacturer. Visual evaluation on a thorax acquisition also showed a good geometrical agreement between simulated and real projections.

CONCLUSIONS

Results showed an excellent matching with simulations, supporting the usefulness of XAP-Lab for the design of new acquisition protocols with non-standard geometries.

摘要

背景与目的

数字 X 射线探测器的出现,加上新型机器人硬件和重建算法的发展,为常规放射学系统提供 3D 功能提供了机会。这将基于使用非标准几何配置获取有限数量的投影。这些技术的多功能性非常大,使得在 CT 系统几乎不可用的情况下,例如在手术中或 ICU 中,或者在儿科中关键是减少辐射剂量的情况下,引入断层摄影成为可能。计算机模拟是在将这些技术实际应用于真实系统之前探索这些可能性的宝贵工具。现有的软件工具通常仅模拟标准采集协议,例如具有圆形轨迹的锥束,从而不允许用户评估更复杂的投影几何形状。本工作的目的是设计一种能够设计具有灵活投影几何形状的采集协议的模拟工具。

方法

我们介绍了 XAP-Lab,这是一种用于设计具有灵活轨迹的 X 射线采集协议的软件工具。对于通过图形用户界面定义的给定投影几何形状,它允许用户使用 GPU 加速内核模拟投影,可视化扫描视场并估计总辐射剂量。然后可以使用适当的格式导出完整的采集协议,以便在真实系统上使用。我们通过优化断层合成协议并使用 SEDECAL NOVA FA 射线照相系统和用于定量和定性评估的体模进行真实采集来验证结果,对软件进行了测试。

结果

使用体模进行的定量评估显示,每个位置的平均误差均低于 4mm,低于制造商规定的系统允许的±5mm 公差。对胸部采集的视觉评估也显示了模拟和真实投影之间的良好几何一致性。

结论

结果与模拟非常吻合,支持 XAP-Lab 在设计具有非标准几何形状的新采集协议方面的有用性。

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