Department of Radiology, Seoul National University Hospital, Jongno-gu, Seoul, Korea.
Department of Radiology, Seoul National University Hospital, Jongno-gu, Seoul, Korea.
Ultrasound Med Biol. 2019 Oct;45(10):2688-2696. doi: 10.1016/j.ultrasmedbio.2019.06.411. Epub 2019 Jul 15.
This study was aimed at evaluating the intra-observer repeatability of shear wave dispersion imaging (SWDI) for evaluation of non-alcoholic fatty liver disease and assessing inter-observer repeatability in asymptomatic volunteers, using a commercial ultrasound system. This prospective study was approved by our institutional review board and informed consent was obtained from all patients. In group I composed of patients with suspected or alleged non-alcoholic fatty liver disease (n = 71), two sessions of SWDI were performed by one radiologist for evaluation of intra-observer repeatability. In group II composed of asymptomatic volunteers (n = 19), three independent sessions were performed by three radiologists. Intra-observer and inter-observer repeatability was assessed using intra-class correlation coefficients (ICCs). For intra-observer repeatability, the ICC was 0.955 (95% confidence interval: 0.926-0.973), and subgroup analysis revealed that body mass index, ultrasound steatosis grade and liver function test abnormalities did not affect ICCs. The ICC for inter-observer repeatability was 0.800 (95% confidence interval: 0.572-0.916). Thus, SWDI had excellent intra-and inter-observer repeatability.
本研究旨在评估使用商业超声系统的剪切波弹性成像（SWE）在评估非酒精性脂肪性肝病中的观察者内重复性，并评估无症状志愿者中的观察者间重复性。这项前瞻性研究得到了我们机构审查委员会的批准，并获得了所有患者的知情同意。在由疑似或被指控患有非酒精性脂肪性肝病的患者组成的 I 组（n=71）中，一位放射科医生进行了两次 SWE 检查，以评估观察者内重复性。在由无症状志愿者组成的 II 组（n=19）中，三位放射科医生进行了三次独立的 SWE 检查。使用组内相关系数（ICC）评估观察者内和观察者间重复性。对于观察者内重复性，ICC 为 0.955（95%置信区间：0.926-0.973），亚组分析表明，体重指数、超声脂肪变性程度和肝功能试验异常不影响 ICC。观察者间重复性的 ICC 为 0.800（95%置信区间：0.572-0.916）。因此，SWE 具有良好的观察者内和观察者间重复性。
