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[敏感性皮肤,反应性皮肤]

[Sensitive skin, reactive skin].

作者信息

Misery L

机构信息

Chef du service de dermatologie, CHU de Brest, 2, avenue Foch, 29609 Brest cedex, France; Directeur du laboratoire de neurosciences de l'Université de Brest (EA4685), 6, avenue le Gorgeu, CS 93837, 29238 Brest cedex 3.

出版信息

Ann Dermatol Venereol. 2019 Sep;146(8-9):585-591. doi: 10.1016/j.annder.2019.05.007. Epub 2019 Jul 15.

Abstract

Sensitive skin (or reactive skin) is defined as a syndrome involving the onset of unpleasant sensations (stinging sensation, burning sensation, pain, pruritus, tingling) in response to stimuli that do not normally produce such sensations. These unpleasant sensations cannot be accounted for by lesions attributable to any specific skin disease. The skin may appear normal or erythema may be present. Sensitive skin can occur on any part of the skin but particularly affects the face. Sensitive skin is very common and affects around half of the population to different degrees. The diagnosis is based primarily on clinical examination. The physiopathology of the condition is becoming better known: it appears to be caused by hyperreactivity of the cutaneous nervous system and is associated in particular with activation of sensorial proteins present on keratinocytes and nerve endings. However, there is still no consensus regarding treatment.

摘要

敏感性皮肤(或反应性皮肤)被定义为一种综合征,即皮肤在受到通常不会产生此类感觉的刺激后,会出现不愉快的感觉(刺痛感、烧灼感、疼痛、瘙痒、刺痛)。这些不愉快的感觉不能用任何特定皮肤病引起的病变来解释。皮肤可能看起来正常,也可能出现红斑。敏感性皮肤可发生在皮肤的任何部位,但面部尤其容易受到影响。敏感性皮肤非常常见,大约影响一半的人群,程度各不相同。诊断主要基于临床检查。这种情况的生理病理学正逐渐为人所知:它似乎是由皮肤神经系统的反应过度引起的,尤其与角质形成细胞和神经末梢上存在的感觉蛋白的激活有关。然而,在治疗方面仍未达成共识。

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