Daya M R, Burton B T, Schleiss M R, DiLiberti J H
Division of Emergency Medicine, Oregon Health Sciences University, Portland 97201.
Ann Emerg Med. 1988 Jun;17(6):646-8. doi: 10.1016/s0196-0644(88)80409-8.
A 5-year-old 20-kg boy developed grand mal seizures following application of 2 mL of tetracaine-adrenalin-cocaine to an oral mucosa laceration. Diazepam 6 mg IV followed by 195 mg phenobarbital was required to terminate the seizures. The patient was transferred to a pediatric intensive care unit for further evaluation and treatment. A toxicology screen obtained after transfer was positive only for diazepam and phenobarbital. The child remained lethargic for several hours but otherwise had a normal neurological examination. Brain computed tomography was normal. Anticonvulsant medication was discontinued prior to discharge and the child had no subsequent seizures.
一名20公斤重的5岁男孩在口腔黏膜裂伤处涂抹2毫升丁卡因-肾上腺素-可卡因后发生癫痫大发作。静脉注射6毫克地西泮，随后注射195毫克苯巴比妥才终止了癫痫发作。该患者被转至儿科重症监护病房进行进一步评估和治疗。转院后进行的毒理学筛查仅显示地西泮和苯巴比妥呈阳性。该患儿持续嗜睡数小时，但其他方面神经系统检查正常。脑部计算机断层扫描正常。出院前停用了抗惊厥药物，该患儿随后未再发生癫痫发作。
