Murakami Taiki, Tanishima Shinji, Takeda Chikako, Kato Shinsuke, Nagashima Hideki
Division of Orthopedic Surgery, Department of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8504, Japan.
Division of Neuropathology, Department of Pathology, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8504, Japan.
Yonago Acta Med. 2019 Jun 20;62(2):232-235. doi: 10.33160/yam.2019.06.008. eCollection 2019 Jun.
Meningiomas constitute approximately 25% of primary spinal cord tumors, and 1% to 5% are calcified. Ossification is a rare event and the etiology of ossification in meningiomas is not well known. We present the case of a 29-year-old female with a rare case of ossified thoracic spinal metaplastic meningioma. The tumor was successfully resected, and pathology confirmed ossified metaplastic meningioma. On histopathological examination, only mature bone tissue and tumor cells were present in the region containing no psammoma bodies, suggesting that the tumor cells had transitioned to mature osteocytes.
脑膜瘤约占原发性脊髓肿瘤的25%，其中1%至5%为钙化型。骨化是一种罕见情况，脑膜瘤骨化的病因尚不清楚。我们报告一例29岁女性患有罕见的胸椎骨化性化生型脑膜瘤。肿瘤成功切除，病理证实为骨化性化生型脑膜瘤。组织病理学检查显示，在不含砂粒体的区域仅存在成熟骨组织和肿瘤细胞，提示肿瘤细胞已转变为成熟骨细胞。
