Tahir Mohammad, Usmani Nida, Ahmad Faiz U, Salmani Sueba, Sharma Manish S
Catholic Health System, State University of New York at Buffalo, Internal Medicine, 565 Abbott Rd, Mercy Hospital of Buffalo, Buffalo, New York, 14220, USA.
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.11.2008.1186. Epub 2009 Apr 14.
Meningiomas constitute about 25% of primary spinal tumours and 1% to 5% of them are calcified. Ossification is a rare event and is rarely reported. Here, the case of a 40-year-old woman who had dorsal spinal cord meningioma (globular variety) at the T(6) vertebral level is reported; the meningioma showed a nidus of T2 weighting hypointensity on MRI as well as a bony chip inside the tumour intraoperatively. The tumour was successfully resected. Though the aetiology of ossification in the meningioma is not well known, metaplasia of arachnoid cells/dystrophic calcification may be the cause. Ossified meningiomas are more difficult to resect than the usual variety. Hypointensity inside tumour in T2-weighted images of MRI should make the surgeon suspicious of this condition, which may in some cases complicate tumour resection.
脑膜瘤约占原发性脊柱肿瘤的25%，其中1%至5%会发生钙化。骨化是一种罕见情况，鲜有报道。在此，报告一例40岁女性病例，其在T(6)椎体水平患有脊髓背侧脑膜瘤（球状型）；该脑膜瘤在MRI上显示为T2加权低信号灶，术中还发现肿瘤内有一块骨碎片。肿瘤成功切除。虽然脑膜瘤骨化的病因尚不清楚，但蛛网膜细胞化生/营养不良性钙化可能是其原因。骨化性脑膜瘤比普通类型更难切除。MRI的T2加权图像上肿瘤内部的低信号应使外科医生怀疑这种情况，在某些情况下这可能会使肿瘤切除复杂化。
