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来自生长于撒丁岛(意大利)的 L. 和 L. 的精油的抗真菌活性。

Antifungal activity of essential oil from L. and L. growing wild in Sardinia island (Italy).

机构信息

Department of Chemical and Geological Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, CA, Italy.

State Institute of Higher Education "Michele Giua", Cagliari, Italy.

出版信息

Nat Prod Res. 2021 Mar;35(6):993-999. doi: 10.1080/14786419.2019.1610755. Epub 2019 Jul 19.

Abstract

This study aims to evaluate the antifungal activity of L. and L. from Sardinia and to assess their efficacy on virulence factors for , particularly on the inhibition of the germ tube formation. The major compounds of the essential oils were carvone (62.9%) for and pulegone (86.2%) for . The essential oil from showed a more preeminent effect against and the dermatophytes and (0.32 μL/mL). Both oils were very effective in inhibiting germ tube formation, at doses well below their MIC (0.16 μL/mL).

摘要

本研究旨在评估来自撒丁岛的 L. 和 L. 的抗真菌活性,并评估它们对 的毒力因子的功效,特别是对抑制芽管形成的功效。精油的主要化合物为香芹酮(62.9%)和胡椒酮(86.2%)。 精油对 和皮肤真菌 和 (0.32 μL/mL)具有更突出的抑制作用。两种油在低于其 MIC(0.16 μL/mL)的剂量下对 芽管形成的抑制作用非常有效。

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