Department of Chemical and Geological Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, CA, Italy.
State Institute of Higher Education "Michele Giua", Cagliari, Italy.
Nat Prod Res. 2021 Mar;35(6):993-999. doi: 10.1080/14786419.2019.1610755. Epub 2019 Jul 19.
This study aims to evaluate the antifungal activity of L. and L. from Sardinia and to assess their efficacy on virulence factors for , particularly on the inhibition of the germ tube formation. The major compounds of the essential oils were carvone (62.9%) for and pulegone (86.2%) for . The essential oil from showed a more preeminent effect against and the dermatophytes and (0.32 μL/mL). Both oils were very effective in inhibiting germ tube formation, at doses well below their MIC (0.16 μL/mL).
本研究旨在评估来自撒丁岛的 L. 和 L. 的抗真菌活性，并评估它们对 的毒力因子的功效，特别是对抑制芽管形成的功效。精油的主要化合物为香芹酮（62.9%）和胡椒酮（86.2%）。 精油对 和皮肤真菌 和 （0.32 μL/mL）具有更突出的抑制作用。两种油在低于其 MIC（0.16 μL/mL）的剂量下对 芽管形成的抑制作用非常有效。
