School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.
Hong Kong Bioinformatics Centre, The Chinese University of Hong Kong, Shatin, Hong Kong.
Curr Protein Pept Sci. 2020;21(2):114-123. doi: 10.2174/1389203720666190719150432.
Mites and ticks are associated with many human diseases including allergic diseases and scabies. With the recent advances in the high throughput DNA sequencing technology, many mitochondrial nuclear genomes of these species have been sequenced and the resulting genomic resources will certainly provide novel insights for the future investigation of the functionally important proteins and peptides in these species. In this mini-review, the current situation of mite and tick genomes is described and the future perspectives for the application of the genomic resources are discussed, especially including the novel identification and structural analysis of allergens.
螨和蜱与许多人类疾病有关，包括过敏疾病和疥疮。随着高通量 DNA 测序技术的最新进展，这些物种的许多线粒体核基因组已经被测序，由此产生的基因组资源必将为这些物种中功能重要的蛋白质和肽的未来研究提供新的见解。在这篇迷你综述中，描述了螨和蜱的基因组现状，并讨论了基因组资源的应用前景，特别是包括过敏原的新鉴定和结构分析。
