基于锥形束 CT 的牙髓腔容积的年龄和性别推断：巴西样本中公式的建立和验证。
Age and sex estimation based on pulp cavity volume using cone beam computed tomography: development and validation of formulas in a Brazilian sample.
机构信息
Forensic Odontology Service, Afrânio Peixoto Legal Medicine Institute, Rio de Janeiro, Brazil.
Department of Social Odontology, Legal Odontology Division, Piracicaba Dental School, University of Campinas, São Paulo, Brazil.
出版信息
Dentomaxillofac Radiol. 2019 Oct;48(7):20190053. doi: 10.1259/dmfr.20190053. Epub 2019 Aug 1.
OBJECTIVES
To develop and validate formulas for age and sex estimation based on the pulp cavity volume of teeth using cone beam CT.
METHODS
The sample was composed of 116 cone beam CT scans from Brazilian individuals of both sexes, ranging in age from 13 to 70 years. A total of 232 teeth (upper central incisors and canines) were evaluated. Two calibrated examiners determined pulp cavity volumes using the ITK-SNAP software. Pearson's correlation test was used to assess the correlation between chronological age and pulp volume. Linear and logistic regression models were developed for age and sex estimation, respectively, and were validated in another sample of 72 teeth.
RESULTS
Pearson's correlation coefficients between age and pulp volume were negative and significant ( < 0.0001) for both teeth ( = -0.8782 for central incisors and = -0.8738 for canines). The age estimation formulas showed good determination coefficients (adjusted R² = 0.7614 to 0.8367). For sex estimation, when the age was known, the coefficients were also good (adjusted R² = 0.649 to 0.812). However, when the age was unknown, the coefficients of the sex estimation formulas were low (adjusted R² = 0.047 to 0.393). Validation showed high accuracy of age estimation in individuals older than 35 years, as well as high accuracy of sex estimation when the age was known.
CONCLUSIONS
Our formulas provided excellent results and can be applied to the Brazilian population. The best results were observed for age estimation in females and for sex estimation when the age was known.
目的
利用锥形束 CT 开发和验证基于牙髓腔容积的年龄和性别估计公式。
方法
该样本由来自巴西的 116 名男女个体的锥形束 CT 扫描组成，年龄在 13 至 70 岁之间。共评估了 232 颗牙齿（上颌中切牙和尖牙）。两名经过校准的检查人员使用 ITK-SNAP 软件确定牙髓腔容积。使用 Pearson 相关检验评估年龄与牙髓容积之间的相关性。分别为年龄和性别估计开发了线性和逻辑回归模型，并在另一组 72 颗牙齿的样本中进行了验证。
结果
年龄与牙髓容积之间的 Pearson 相关系数为负且显著（<0.0001），对于两颗牙齿（中切牙为-0.8782，尖牙为-0.8738）均如此。年龄估计公式显示出良好的确定系数（调整后的 R²=0.7614 至 0.8367）。对于性别估计，当年龄已知时，系数也很好（调整后的 R²=0.649 至 0.812）。然而，当年龄未知时，性别估计公式的系数较低（调整后的 R²=0.047 至 0.393）。验证表明，对于年龄大于 35 岁的个体，年龄估计具有很高的准确性，并且在已知年龄时性别估计的准确性也很高。
结论
我们的公式提供了出色的结果，可应用于巴西人群。对于女性的年龄估计和已知年龄时的性别估计，结果最佳。
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