哪些因素决定了在感染性全踝关节置换术（TAA）患者的水泥间隔器中添加抗生素的类型和剂量？
What Determines the Type and Dose of Antibiotic That Is Needed to Be Added to the Cement Spacer in Patients With Infected Total Ankle Arthroplasty (TAA)?
机构信息
1 Rothman Orthopaedic Institute, Media, PA, USA.
2 Codivilla-Putti Institutes and Italian National Department of the Bone Infections, Bologna, Italy.
出版信息
Foot Ankle Int. 2019 Jul;40(1_suppl):48S-52S. doi: 10.1177/1071100719861098.
RECOMMENDATION
We recommend tailoring the antibiotic in cement spacers to the infecting organism if it has been identified, as is typically done in total knee and hip arthroplasty. Otherwise, broad-spectrum antibiotics may be utilized. Medical comorbidities should always be considered, especially with regard to renal function and allergy profile. A thermostable antibiotic should be added to cement.
LEVEL OF EVIDENCE
Consensus.
DELEGATE VOTE
Agree: 100%, Disagree: 0%, Abstain: 0% (Unanimous, Strongest Consensus).
建议
如果已经确定感染病原体，可根据病原体定制抗生素骨水泥间隔物，这在全膝关节和髋关节置换术中通常是这样做的。否则，可以使用广谱抗生素。应始终考虑合并的内科疾病，尤其是肾功能和过敏史。应在骨水泥中添加热稳定性抗生素。
循证医学等级
共识。
代表投票
同意：100%，不同意：0%，弃权：0%（一致通过，最强共识）。
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