Department of Orthopedics, Clinical Medical College of Yangzhou University, Yangzhou, 225001, China.
Department of Orthopedics, Northern Jiangsu People's Hospital, Clinical Medical School, Yangzhou University, 98 West Nangtong Road, Yangzhou, 225001, Jiangsu, China.
J Orthop Surg Res. 2019 Jul 19;14(1):228. doi: 10.1186/s13018-019-1273-z.
Vertebroplasty is the most widely used method for treating osteoporotic vertebral compression fractures (OVCF). During this procedure, bone cement is injected into the vertebral body. Fracture and additional fractures can occur adjacent to the treatment site. Thus, we studied factors causing such vertebral fractures after vertebroplasty and calculated the appropriate amount of bone cement to inject.
From September 2012 to March 2016, 187 patients with OVCF undergoing vertebroplasty were selected, and 112 patients with complete follow-up information were selected. Of these, 28 had adjacent vertebral fractures (refracture group) during the follow-up period, and 84 patients had no adjacent vertebral fractures (control group). Then, sex, age, body weight, bone mineral density (BMD), and bone cement injection (bone cement injection volume and bone fracture vertebral volume percent) were compared.
All patients had significant pain relief within 24 h (preoperative and postoperative [24 h later] VAS scores were 7.4 ± 0.8 and 2.3 ± 0.5, respectively). The age and weight were not statistically significantly different (P > 0.05). BMD values were statistically significantly different between groups as was sex (P < 0.05).
Bone cement injection volume, BMD values, and sex were statistically significantly related to adjacent vertebral fractures after vertebroplasty, and cement injection volumes exceeding 40.5% caused adjacent vertebral fractures.
椎体成形术是治疗骨质疏松性椎体压缩性骨折（OVCF）最广泛应用的方法。在该过程中，将骨水泥注入椎体。在治疗部位附近可能会发生骨折和其他骨折。因此，我们研究了椎体成形术后导致此类椎体骨折的因素，并计算了适当的骨水泥注射量。
2012 年 9 月至 2016 年 3 月，选择 187 例 OVCF 行椎体成形术患者，其中 112 例具有完整随访资料，其中 28 例在随访期间发生相邻椎体骨折（再骨折组），84 例无相邻椎体骨折（对照组）。然后比较性别、年龄、体重、骨密度（BMD）和骨水泥注射量（骨水泥注射量和骨折椎体体积百分比）。
所有患者术后 24 小时内疼痛均明显缓解（术前和术后 24 小时的 VAS 评分分别为 7.4±0.8 和 2.3±0.5）。年龄和体重无统计学差异（P>0.05）。组间 BMD 值和性别存在统计学差异（P<0.05）。
骨水泥注射量、BMD 值和性别与椎体成形术后相邻椎体骨折有统计学显著相关性，骨水泥注射量超过 40.5%可导致相邻椎体骨折。
