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单侧经皮椎体骨水泥分布在骨质疏松性胸腰椎椎体压缩骨折修复中的临床疗效分析

Clinical effect analysis of unilateral percutaneous vertebral cement distribution in the repair of osteoporotic thoracolumbar vertebral compression fractures.

作者信息

Yuntao Liu, Haibier Abuduwupuer, Kayierhan Aiben, Liang Ma, Abudukelimu Yimuran, Aximu Alimujiang, Abudurexiti Tuerhongjiang, Xiangyu Meng

机构信息

Minimally Invasive Spine Surgery, Sixth Afliated Hospital of Xinjiang Medical University, Orthopaedic Hospital of Xinjiang Uygur Autonomous Region, No.39 Wuxing Road, Urumqi, Xinjiang Uygur Autonomous Region, 830002, People's Republic of China.

出版信息

BMC Surg. 2025 Mar 5;25(1):90. doi: 10.1186/s12893-025-02820-0.

DOI:10.1186/s12893-025-02820-0
PMID:40045301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11881425/
Abstract

BACKGROUND

Osteoporotic vertebral fractures and their complications pose increasing risks to the elderly. The purpose of this study was to evaluate the clinical efficacy of unilateral percutaneous vertebroplasty in patients with osteoporotic vertebral compression fractures (OVCF) by assessing postoperative cement distribution.

OBJECTIVE

This study aimed to investigate the impact of cement distribution on the efficacy of vertebral compression fracture repair to provide effective preventive and therapeutic measures, prevent postoperative vertebral re-fracture, and improve surgical outcomes.

METHODS

A total of 170 patients who underwent unilateral percutaneous vertebroplasty at our hospital from January 2020 to December 2022 were selected. Based on the postoperative X-ray cement distribution morphology, they were divided into the good distribution group (n = 87) and the poor dispersion group (n = 83). The basic information of patients, surgery-related indicators including operation time, total hospitalization costs, postoperative hospitalization time, cement injection volume, visual analog scale (VAS) for back pain, Oswestry Disability Index (ODI) for back pain, vertebral height restoration rate, local kyphotic angle of the vertebra, and incidence of re-fracture of injured and adjacent vertebrae were compared between the two groups, and the follow-up results of all patients were recorded.

RESULTS

There were no significant differences in age, gender, body mass index, fracture days, menopausal age of female patients, bone density T value, medical history, smoking history, alcohol history, and surgical segments between the two groups (P > 0.05). The VAS scores for back pain at 1 month and 1 year postoperatively were significantly lower in the good distribution group than in the poor dispersion group, with statistical significance (P < 0.05). The good distribution group had a significantly lower incidence of re-fracture of injured vertebrae and overall fracture incidence than the poor dispersion group (P < 0.05). There were no statistically significant differences in operation time, cement dosage, cement leakage, postoperative hospitalization time, adjacent vertebral fractures, postoperative vertebral height restoration rate, VAS scores for back pain at preoperative and 1 week postoperative, and ODI at preoperative, 1 week, 1 month, and 1 year postoperative between the two groups (P > 0.05).

CONCLUSION

Compared with the poor dispersion group, patients in the cement distribution group achieved better short-term clinical efficacy, and long-term prognosis effects are still under observation. Moreover, the cement good distribution group significantly reduced the incidence of re-fracture of injured vertebrae and overall fracture incidence, thereby achieving better surgical outcomes.

摘要

背景

骨质疏松性椎体骨折及其并发症给老年人带来的风险日益增加。本研究的目的是通过评估术后骨水泥分布情况,评价单侧经皮椎体成形术治疗骨质疏松性椎体压缩骨折(OVCF)患者的临床疗效。

目的

本研究旨在探讨骨水泥分布对椎体压缩骨折修复疗效的影响,以提供有效的预防和治疗措施,预防术后椎体再骨折,提高手术效果。

方法

选取2020年1月至2022年12月在我院接受单侧经皮椎体成形术的170例患者。根据术后X线骨水泥分布形态,将其分为分布良好组(n = 87)和弥散不良组(n = 83)。比较两组患者的基本信息、手术相关指标,包括手术时间、总住院费用、术后住院时间、骨水泥注入量、背痛视觉模拟评分(VAS)、背痛Oswestry功能障碍指数(ODI)、椎体高度恢复率、椎体局部后凸角以及伤椎和相邻椎体再骨折发生率,并记录所有患者的随访结果。

结果

两组患者在年龄、性别、体重指数、骨折天数、女性患者绝经年龄、骨密度T值、病史、吸烟史、饮酒史及手术节段方面比较,差异均无统计学意义(P > 0.05)。分布良好组术后1个月和1年的背痛VAS评分显著低于弥散不良组,差异有统计学意义(P < 0.05)。分布良好组伤椎再骨折发生率和总体骨折发生率均显著低于弥散不良组(P < 0.05)。两组患者在手术时间、骨水泥用量、骨水泥渗漏、术后住院时间、相邻椎体骨折、术后椎体高度恢复率、术前及术后1周背痛VAS评分以及术前、术后1周、1个月和1年的ODI方面比较,差异均无统计学意义(P > 0.05)。

结论

与弥散不良组相比,骨水泥分布良好组患者获得了较好的短期临床疗效,长期预后效果仍在观察中。此外,骨水泥分布良好组显著降低了伤椎再骨折发生率和总体骨折发生率,从而取得了较好的手术效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/5877b87a79ee/12893_2025_2820_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/167cc27d3937/12893_2025_2820_Fig1_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/8d57317b9998/12893_2025_2820_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/01ee3d2b2514/12893_2025_2820_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/5877b87a79ee/12893_2025_2820_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/167cc27d3937/12893_2025_2820_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/cc063b1c62e8/12893_2025_2820_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/498806f83190/12893_2025_2820_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/8d57317b9998/12893_2025_2820_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/01ee3d2b2514/12893_2025_2820_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee0/11881425/5877b87a79ee/12893_2025_2820_Fig6_HTML.jpg

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