Beverina Ivo, Brando Bruno
Blood Transfusion Center, Legnano General Hospital, Legnano, Milano, Italy.
Blood Transfusion Center, Legnano General Hospital, Legnano, Milano, Italy.
Transfus Apher Sci. 2019 Oct;58(5):688-692. doi: 10.1016/j.transci.2019.07.006. Epub 2019 Jul 9.
The aim of this study was to assess the general prevalence and the treatment policy of anemic patients referring to the Emergency Department (ED) of a tertiary care Hospital during 2015.
The full blood cell count data from patients admitted to the ED for any reason,excepted for those with massive hemorrhage and multiple trauma, were studied. The prevalence of anemic patients and the degree of anemia were recorded, along with the transfusion policy applied. Transfusion appropriateness was retrospectively evaluated with a specific algorithm, that also considered the administered volume of red blood cells. A particular focus was made on patients with microcytosis about the physicians' awareness of the underlying iron deficiency and the consequent iron prescription.
In a group of 22,329 patients the overall prevalence of anemia was 27.5% (6144 patients). Among the anemic patients, 281 / 6144 (4.6%) were transfused. The applied transfusion policy, as evaluated with the algorithm showed an overall good level of appropriateness (74.5% of transfusion episodes) but the appropriateness of the administered red blood cell mass was low (8.8%), due to over-transfusion. In microcytic transfused patients (mean MCV 69.0 ± SD 9.1), the iron balance tests were rarely ordered (22 patients out of 98-22.2%) and intravenous iron was prescribed in only 9 patients out of the 98 eligible (9.2%).
The Patient Blood Management principles should be applied also in the ED setting, to promote a more appropriate and effective clinical approach to anemic patients.
本研究旨在评估2015年期间转诊至一家三级医院急诊科的贫血患者的总体患病率及治疗策略。
对因任何原因入住急诊科的患者(大出血和多发伤患者除外)的全血细胞计数数据进行研究。记录贫血患者的患病率及贫血程度,以及所应用的输血策略。采用一种特定算法对输血合理性进行回顾性评估,该算法还考虑了红细胞的输注量。特别关注小细胞性贫血患者,了解医生对潜在缺铁情况的认知以及相应的铁剂处方情况。
在一组22329例患者中,贫血的总体患病率为27.5%(6144例患者)。在贫血患者中,281/6144(4.6%)接受了输血治疗。通过该算法评估所应用的输血策略显示,总体合理性水平良好(74.5%的输血事件),但由于过度输血,所输注红细胞量的合理性较低(8.8%)。在小细胞性贫血输血患者中(平均MCV 69.0±标准差9.1),很少进行铁平衡检查(98例患者中有22例 - 22.2%),在98例符合条件的患者中,仅9例患者开具了静脉铁剂处方(9.2%)。
患者血液管理原则也应在急诊科环境中应用,以促进对贫血患者采取更合适、有效的临床治疗方法。