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儿童外科疾病的流行病学与死亡率:来自乌干达一家三级医疗中心的见解

Epidemiology and mortality of pediatric surgical conditions: insights from a tertiary center in Uganda.

作者信息

Cheung Maija, Kakembo Nasser, Rizgar Nensi, Grabski David, Ullrich Sarah, Muzira Arlene, Kisa Phyllis, Sekabira John, Ozgediz Doruk

机构信息

Department of Surgery, Yale University School of Medicine, 330 Cedar Street, FMB 107, New Haven, CT, 06510, USA.

Department of Surgery, Makerere University, Mulago Hospital, Kampala, Uganda.

出版信息

Pediatr Surg Int. 2019 Nov;35(11):1279-1289. doi: 10.1007/s00383-019-04520-2. Epub 2019 Jul 19.

Abstract

INTRODUCTION/PURPOSE: The burden of pediatric surgical disease is largely unknown in low- and middle-income countries such as Uganda where access to care is limited.

METHODS

Implementation of a locally led database in January 2012 at a Ugandan tertiary referral hospital, and review of 3465 prospectively collected pediatric surgical admissions from January 2012 to August 2016.

RESULTS

2090 children (60.3%) underwent surgery during admission. 59% were male and 41% female. 28.6% of admissions were in neonates and 50.4% were in children less than 1 year old. Congenital anomalies including Hirschsprung's, anorectal malformations, intestinal atresias, omphalocele, and gastroschisis were the most common diagnoses (38.6%) followed by infections (15.0%) and tumors (8.6%). Mortality rates were substantially higher than those of high-income countries; for example, gastroschisis and intussusception had mortality rates of 90.1% and 19.7%, respectively. Post-operative mortality was highest in the congenital anomalies group (15.0%).

CONCLUSION

There is a high burden of infant congenital anomalies with higher mortality rates compared to high-income countries. The unit performs primarily specialized procedures appropriate for a tertiary center. We hope that these data will facilitate evaluation of ongoing quality improvement and capacity-building initiatives.

摘要

引言/目的:在乌干达等中低收入国家,儿科外科疾病的负担很大程度上尚不明确,这些国家的医疗服务获取受限。

方法

2012年1月在乌干达一家三级转诊医院实施了一个由当地主导的数据库,并回顾了2012年1月至2016年8月前瞻性收集的3465例儿科外科住院病例。

结果

2090名儿童(60.3%)在住院期间接受了手术。其中59%为男性,41%为女性。28.6%的住院患者为新生儿,50.4%为1岁以下儿童。先天性畸形包括先天性巨结肠、肛门直肠畸形、肠闭锁、脐膨出和腹裂是最常见的诊断(38.6%),其次是感染(15.0%)和肿瘤(8.6%)。死亡率显著高于高收入国家;例如,腹裂和肠套叠的死亡率分别为90.1%和19.7%。先天性畸形组术后死亡率最高(1)。

结论

与高收入国家相比,婴儿先天性畸形负担沉重,死亡率更高。该科室主要开展适合三级中心的专科手术。我们希望这些数据将有助于评估正在进行的质量改进和能力建设举措。

原文中“Post-operative mortality was highest in the congenital anomalies group (15.0%).”这里的“1”可能有误,根据上下文推测可能是“15.0%”,译文已按此修正。

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