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中国人群精神分裂症患者功能康复的最佳住院时长:一项真实世界研究。

The Optimal Length of Hospitalization for Functional Recovery of Schizophrenia Patients, a Real-World Study in Chinese People.

机构信息

Peking University Huilongguan Clinical Medical School, Beijing Huilongguan Hospital, Beijing, 100096, People's Republic of China.

Peking University Sixth Hospital, Peking University Institute of Mental Health, Key Laboratory of Mental Health, Ministry of Health (Peking University), Beijing, 100191, People's Republic of China.

出版信息

Psychiatr Q. 2019 Sep;90(3):661-670. doi: 10.1007/s11126-019-09658-9.

DOI:10.1007/s11126-019-09658-9
PMID:31327081
Abstract

This study investigated the relationship between the activities of daily living and the length of hospitalization to determine the optimal length of hospitalization for patients with schizophrenia. We collected information from all schizophrenia patients discharged in Peking University Huilongguan Clinical Medical School from January 1, 2015 to December 31, 2015. A total of 1967 patients were enrolled in this study. The Chinese version of the modified Barthel index (MBI-C) was used to assess patients' actual performance on activities of daily living. We used the paired samples t-test to compare MBI-C scores at admission and discharge and performed correlation analysis to find the trend of MBI-C change with length of hospitalization. The average length of hospitalization was 73.3 ± 42.2 days. There were significant differences between the MBI-C scores at the time of discharge from hospital compared with those at the time of admission to the hospital (93.4 ± 11.2 vs. 88.7 ± 11.8; P < 0.001). Taking the length of hospitalization as the grouping boundary value, the correlation analysis of the subgroup found that below a minimum of 20 days, the improvement in the MBI-C scores increased with the increase of length of hospitalization, and above a maximum of 50 days, the improvement in the MBI-C scores decreased with the increase of length of hospitalization. The optimal length of hospitalization for patients with schizophrenia may lie between 20 and 50 days, with regard to the recovery of daily living function.

摘要

本研究旨在探讨日常生活活动能力与住院时间的关系,以确定精神分裂症患者的最佳住院时间。我们收集了 2015 年 1 月 1 日至 12 月 31 日期间在北京大学回龙观临床医学院出院的所有精神分裂症患者的信息。共有 1967 名患者纳入本研究。采用改良 Barthel 指数(MBI-C)中文版评估患者日常生活活动的实际表现。我们使用配对样本 t 检验比较入院和出院时的 MBI-C 评分,并进行相关性分析,以发现 MBI-C 随住院时间变化的趋势。平均住院时间为 73.3±42.2 天。出院时的 MBI-C 评分与入院时相比有显著差异(93.4±11.2 与 88.7±11.8;P<0.001)。以住院时间为分组边界值,对亚组进行相关性分析发现,在 20 天以下时,MBI-C 评分的改善随住院时间的增加而增加,在 50 天以上时,MBI-C 评分的改善随住院时间的增加而减少。精神分裂症患者的最佳住院时间可能在 20 至 50 天之间,这有利于其日常生活功能的恢复。

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