Cheng Peng, Wang Lirong, Xu Lizhi, Zhou Ying, Zhang Li, Li Weihui
National Clinical Research Center for Mental Disorders and Department of Psychiatry, The Second Xiangya Hospital of Central South University, Changsha, China.
Xiangya School of Medicine, Xiangya Hospital, Central South University, Changsha, China.
Front Psychiatry. 2022 Jan 24;12:818254. doi: 10.3389/fpsyt.2021.818254. eCollection 2021.
The length of stay (LOS) of patients with schizophrenia has been a wide concern of researchers. Reasonable management of the LOS to achieve a balance between quality of treatment and efficient medical source allocation has become a significant issue in clinical work in psychiatry. Figuring out the factors related to the LOS of schizophrenia patients can help optimize its management by the hospital.
The essential information of patients was obtained from the electronic medical record system. The variables were divided into the following kinds: demographic, clinical, and biochemical. Univariate analysis and multivariate analysis were conducted to find the potential factors related to the LOS of schizophrenia patients. Receiver operating characteristic analyses were conducted to evaluate the accuracy of judging the LOS of the regression model.
A total of 1,160 patients with schizophrenia were enrolled in our research. Our results demonstrated that the status of unmarried (single, separated, divorced, or widowed) and the abnormality of thyroid-stimulating hormone (TSH) were risk factors for the longer LOS of schizophrenia patients. The area under the curve was 0.576, which meant that the regression model had a certain predictive value.
To our knowledge, this research is the first study to analyze the effect of various factors, including the biochemical index, on the LOS of a single type of mental disorder. Marital status and TSH were proven to be related to the LOS of schizophrenia patients. The results of this study provided reference factors of LOS for clinical psychiatry, which will be helpful to the management of hospitalization and in optimizing the allocation of medical sources.
精神分裂症患者的住院时间一直是研究人员广泛关注的问题。合理管理住院时间以在治疗质量和有效医疗资源分配之间取得平衡，已成为精神病学临床工作中的一个重要问题。找出与精神分裂症患者住院时间相关的因素有助于医院优化其管理。
从电子病历系统中获取患者的基本信息。变量分为以下几类：人口统计学、临床和生化指标。进行单因素分析和多因素分析以找出与精神分裂症患者住院时间相关的潜在因素。进行受试者工作特征分析以评估回归模型判断住院时间的准确性。
共有1160例精神分裂症患者纳入本研究。我们的结果表明，未婚状态（单身、分居、离婚或丧偶）和促甲状腺激素（TSH）异常是精神分裂症患者住院时间较长的危险因素。曲线下面积为0.576，这意味着回归模型具有一定的预测价值。
据我们所知，本研究是首次分析包括生化指标在内的各种因素对单一类型精神障碍住院时间影响的研究。婚姻状况和TSH被证明与精神分裂症患者的住院时间有关。本研究结果为临床精神病学提供了住院时间的参考因素，这将有助于住院管理和优化医疗资源分配。
