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从左心室射血分数到心脏血流动力学:超声心动图在心力衰竭患者评估中的作用。

From left ventricular ejection fraction to cardiac hemodynamics: role of echocardiography in evaluating patients with heart failure.

机构信息

Cardiology Unit and LTTA Centre, University of Ferrara, Viale Aldo Moro 8, 44024 Cona, Ferrara, Italy.

Heart Failure Clinic, Cardiology Department, Centro Hospitalar do Tâmega e Sousa, Penafiel, Portugal.

出版信息

Heart Fail Rev. 2020 Mar;25(2):217-230. doi: 10.1007/s10741-019-09826-w.

DOI:10.1007/s10741-019-09826-w
PMID:31327115
Abstract

In clinical practice heart failure (HF) patients are generally classified on the basis of left ventricular (LV) ejection fraction. This approach, however, has important limitations. According to the definition of HF as a clinical syndrome that results from any impairment of LV filling or ejection of blood, a more articulated hemodynamic categorization of HF patients taking into account both LV forward flow and filling pressure would be desirable. However, the reliability of hemodynamic measures using echocardiographic techniques, which are the most used in current clinical practice for evaluation of HF patients, needs to be clarified. The aim of this article, therefore, is to verify whether echocardiography has acceptable feasibility, accuracy and reproducibility for the noninvasive evaluation of LV hemodynamics. This evaluation is necessary to progress to a hemodynamic characterization of HF patients that would ultimately overcome the HF classification based on ejection fraction.

摘要

在临床实践中,心力衰竭(HF)患者通常根据左心室(LV)射血分数进行分类。然而,这种方法有重要的局限性。根据 HF 作为一种由任何 LV 充盈或血液射血受损引起的临床综合征的定义,更详细的血流动力学分类将有助于考虑 HF 患者的 LV 前向流量和充盈压。然而,目前临床实践中最常用于评估 HF 患者的超声心动图技术的血流动力学测量的可靠性需要澄清。因此,本文的目的是验证超声心动图是否具有可接受的可行性、准确性和可重复性,用于非侵入性评估 LV 血流动力学。这种评估对于推进 HF 患者的血流动力学特征描述是必要的,最终将克服基于射血分数的 HF 分类。

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J Am Soc Echocardiogr. 2018 Jun;31(6):660-663. doi: 10.1016/j.echo.2018.03.002. Epub 2018 May 2.
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Mean Right Atrial Pressure for Estimation of Left Ventricular Filling Pressure in Patients with Normal Left Ventricular Ejection Fraction: Invasive and Noninvasive Validation.
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Cardiovasc Ultrasound. 2025 May 19;23(1):13. doi: 10.1186/s12947-025-00347-1.
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J Inflamm Res. 2025 Mar 12;18:3589-3605. doi: 10.2147/JIR.S512476. eCollection 2025.
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