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当代心源性休克管理:美国心脏协会的科学声明

Contemporary Management of Cardiogenic Shock: A Scientific Statement From the American Heart Association.

出版信息

Circulation. 2017 Oct 17;136(16):e232-e268. doi: 10.1161/CIR.0000000000000525. Epub 2017 Sep 18.

DOI:10.1161/CIR.0000000000000525
PMID:28923988
Abstract

Cardiogenic shock is a high-acuity, potentially complex, and hemodynamically diverse state of end-organ hypoperfusion that is frequently associated with multisystem organ failure. Despite improving survival in recent years, patient morbidity and mortality remain high, and there are few evidence-based therapeutic interventions known to clearly improve patient outcomes. This scientific statement on cardiogenic shock summarizes the epidemiology, pathophysiology, causes, and outcomes of cardiogenic shock; reviews contemporary best medical, surgical, mechanical circulatory support, and palliative care practices; advocates for the development of regionalized systems of care; and outlines future research priorities.

摘要

心原性休克是一种高急症、可能复杂且血流动力学多样化的终末器官低灌注状态,常伴有多器官功能衰竭。尽管近年来生存率有所提高,但患者的发病率和死亡率仍然很高,并且只有少数基于证据的治疗干预措施被认为可以明显改善患者的预后。本关于心原性休克的科学声明总结了心原性休克的流行病学、病理生理学、病因和结局;回顾了当代最佳的药物治疗、手术治疗、机械循环支持和姑息治疗实践;提倡发展区域化的医疗护理系统;并概述了未来的研究重点。

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