Xun Y F, Wang M H, Sun H Y, Guan B
Department of Otolaryngology, the Second Xiangya Hospital of Central South University, Changsha, 410000, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Jul;33(7):643-646. doi: 10.13201/j.issn.1001-1781.2019.07.016.
The aim of this study is to compare the night sleep hypoxia degree and sleep structure of young and middle-aged and elderly patients with OSA, so that PSG has more important application value.A total of 438 patients diagnosed with OSA from February 2017 to January 2019 were selected,including 119 patients in the youth group with an average age of (28.5±5.1）years,and 319 patients in the middle and elderly group with an average age of (45.8±2.7)years.The results recorded by PSG in the two groups were retrospectively analyzed. ①The AHI, ODI, OAI, MAI and ASaO₂of OSA patients in the junior group were significantly higher than those in the middle-aged and elderly group, while CAI was not statistically significant between the two groups (=0.419).②The NREM stage Ⅰ (61.1±4.3)% in the junior group was significantly higher than that in the junior group (53.3±3.4)%.NREM stage Ⅱ (33.2±2.3)% and NREM stage Ⅲ+Ⅳ (4.3±1.3)% in the junior group were higher than those in the middle-aged group (29.2±3.9)% and stage Ⅲ+Ⅳ (2.6±0.9)%, while the percentage of REM stage and microarousal index were not statistically significant between the two groups.③Young OSA patients were associated with hypertension and 47.0% middle-aged and elderly patients were associated with hypertension.There was no statistical difference between the two groups in whether hypertension was associated with hypertension or not.The NREM phase is particularly susceptible to age, and age affects slow wave sleep. The sleep structure of middle-aged and older people demonstrates their sleep characteristics: reduced total sleep time,slow wave sleep,low sleep efficiency,and delayed sleep. The young people's nighttime hypoxia is more serious. AHI,ODI,OAI,MAI,ASaO₂ and other indicators are significantly higher than the middle-aged and elderly people, but the sleep structure 2 groups are similar, indicating that young people have strong sleep physiological compensation and Adjustment ability.
本研究旨在比较青年、中年及老年阻塞性睡眠呼吸暂停（OSA）患者的夜间睡眠缺氧程度及睡眠结构，以使多导睡眠监测（PSG）具有更重要的应用价值。选取2017年2月至2019年1月间确诊为OSA的患者438例，其中青年组119例，平均年龄（28.5±5.1）岁，中年及老年组319例，平均年龄（45.8±2.7）岁。对两组PSG记录结果进行回顾性分析。①青年组OSA患者的呼吸暂停低通气指数（AHI）、氧减指数（ODI）、氧增指数（OAI）、微觉醒指数（MAI）及最低血氧饱和度（ASaO₂）均显著高于中年及老年组，而两组间的中枢性呼吸暂停指数（CAI）差异无统计学意义（P=0.419）。②青年组非快速眼动（NREM）睡眠Ⅰ期（61.1±4.3）%显著高于中年组（53.3±3.4）%。青年组NREM睡眠Ⅱ期（33.2±2.3）%及NREM睡眠Ⅲ+Ⅳ期（4.3±1.3）%高于中年组（29.2±3.9）%及Ⅲ+Ⅳ期（2.6±0.9）%，而两组间快速眼动（REM）睡眠期百分比及微觉醒指数差异无统计学意义。③青年OSA患者合并高血压的比例为47.0%，中年及老年患者合并高血压的比例为47.0%。两组间高血压合并情况差异无统计学意义。NREM睡眠期受年龄影响尤为明显，年龄影响慢波睡眠。中年及老年人的睡眠结构体现出其睡眠特点：总睡眠时间减少、慢波睡眠减少、睡眠效率低下及入睡延迟。青年人夜间缺氧更严重。AHI、ODI、OAI、MAI、ASaO₂等指标显著高于中年及老年人，但两组睡眠结构相似，提示青年人具有较强的睡眠生理代偿及调节能力。
