IBA1 转运蛋白将生长素和细胞分裂素联系起来影响根系结构。
TRANSPORTER OF IBA1 Links Auxin and Cytokinin to Influence Root Architecture.
机构信息
Department of Biology, Washington University, St. Louis, MO 63130, USA.
Institute for Molecular Physiology, Heinrich Heine Universität Düsseldorf, Institute for Biotransformative Molecules (WPI-ITbM), Nagoya University, Nagoya, Japan; Agricultural Biotechnology Research Center, Academia Sinica, Taipei, Taiwan.
出版信息
Dev Cell. 2019 Sep 9;50(5):599-609.e4. doi: 10.1016/j.devcel.2019.06.010. Epub 2019 Jul 18.
Developmental processes that control root system architecture are critical for soil exploration by plants, allowing for uptake of water and nutrients. Conversion of the auxin precursor indole-3-butyric acid (IBA) to active auxin (indole-3-acetic acid; IAA) modulates lateral root formation. However, mechanisms governing IBA-to-IAA conversion have yet to be elucidated. We identified TRANSPORTER OF IBA1 (TOB1) as a vacuolar IBA transporter that limits lateral root formation. Moreover, TOB1, which is transcriptionally regulated by the phytohormone cytokinin, is necessary for the ability of cytokinin to exert inhibitory effects on lateral root production. The increased production of lateral roots in tob1 mutants, TOB1 transport of IBA into the vacuole, and cytokinin-regulated TOB1 expression provide a mechanism linking cytokinin signaling and IBA contribution to the auxin pool to tune root system architecture.
控制根系结构发育的过程对于植物的土壤探索至关重要，这使得植物能够吸收水分和养分。生长素前体吲哚-3-丁酸（IBA）向活性生长素（吲哚-3-乙酸；IAA）的转化调节侧根的形成。然而，控制 IBA 向 IAA 转化的机制尚不清楚。我们发现生长素转运蛋白 1（TOB1）是一种液泡 IBA 转运蛋白，它限制了侧根的形成。此外，TOB1 的转录受植物激素细胞分裂素调控，对于细胞分裂素抑制侧根产生的能力是必需的。TOB1 突变体中侧根的大量产生、TOB1 将 IBA 转运到液泡中，以及细胞分裂素调控的 TOB1 表达，为细胞分裂素信号与 IBA 对生长素库的贡献之间的联系提供了一种机制，从而调节根系结构。
Zotero 插件