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一种用于比色荧光测量电离辐射剂量的纳米凝胶传感器。

A nanogel sensor for colorimetric fluorescence measurement of ionizing radiation doses.

作者信息

Li Wenxiang, Nie Jing, Hu Rui, Zhao Rui, Zhu Weifang, Chen Xinjian, Li Dan, Wang Lei, Hu Liang

机构信息

School for Radiological and Interdisciplinary Sciences (RAD-X), Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions and Jiangsu Provincial Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou, Jiangsu 215123, China.

Department of Radiation Oncology, Suzhou Municipal Hospital, Suzhou, Jiangsu 215008, China.

出版信息

Chem Commun (Camb). 2019 Aug 21;55(65):9614-9617. doi: 10.1039/c9cc03680f. Epub 2019 Jul 22.

Abstract

A polyacrylamide-based nanogel sensor was constructed for spectral and visual colorimetric fluorescence measurement of ionizing radiation doses. The sensor showed a good linear and reproducible response in the dose range of 0-20 Gy with low errors, temperature stability and durability. The sensor was used to detect X-ray-irradiated tumor cell doses.

摘要

构建了一种基于聚丙烯酰胺的纳米凝胶传感器,用于电离辐射剂量的光谱和视觉比色荧光测量。该传感器在0-20 Gy的剂量范围内表现出良好的线性和可重复响应,误差低、具有温度稳定性和耐久性。该传感器用于检测X射线照射的肿瘤细胞剂量。

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