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[使用均苯四甲酸和偏苯三甲酸的剂量测定法。第1部分]

[Dosimetry using pyromellitic acid and trimellitic acid. Part 1].

作者信息

Nadrowitz R

机构信息

Klinik für Strahlentherapie und Nuklearmedizin, Medizinischen Universität zu Lübeck.

出版信息

Strahlenther Onkol. 1994 Mar;170(3):174-9.

PMID:8160099
Abstract

PURPOSE

The intention of the study was to demonstrate that a chemical dosimeter on the basis of fluorescing acids is able to measure ionizing radiation much more sensitively than the Fricke dosimeter.

MATERIALS AND METHODS

As detectors for ionizing radiation pyromellitic acid (1,2,4,5-benzene-tetracarboxylic acid) and trimellitic acid (1,2,4-benzene-tricarboxylic acid) were investigated. Both solutions were exposed to pulsed 10 MV photons. The dose rate and the radiation dose were modified according to the different questions.

RESULTS

The correlation between absorbed dose and intensity of fluorescence was studied from 2 Gy up to doses of 16 Gy. Within this dose range the intensity of fluorescence of the mentioned solutions correlate with the absorbed doses in a single-valued and linear way. The fluorescence of pyromellitic acid is independent of the dose rate in the studied range from 0.6 Gy/min to 5 Gy/min. Detectors with trimellitic acid are able to quantify the absorbed energy of ionising radiation independent of the dose rate from 0.6 Gy/min on, but in contrast to pyromellitic acid only up to 3.8 Gy/min. The stability of the excitation and fluorescence spectra, the fading of the irradiated detectors, the reproducibility of the measured results and the increase of the null value of both solutions qualify for the use of these dosimeters in the clinical routine.

CONCLUSIONS

If further measurements should prove the independence of the presented detectors from the kind of radiation, the radiation quality and the temperature, there is a new possibility to use the specific advantages of chemical dosimeters in a more simple way.

摘要

目的

本研究旨在证明基于荧光酸的化学剂量计能够比弗里克剂量计更灵敏地测量电离辐射。

材料与方法

研究了均苯四甲酸(1,2,4,5 - 苯四羧酸)和偏苯三酸(1,2,4 - 苯三羧酸)作为电离辐射探测器。两种溶液均暴露于脉冲10 MV光子下。根据不同问题改变剂量率和辐射剂量。

结果

研究了2 Gy至16 Gy剂量范围内吸收剂量与荧光强度之间的相关性。在此剂量范围内,上述溶液的荧光强度与吸收剂量呈单值线性相关。在0.6 Gy/min至5 Gy/min的研究范围内,均苯四甲酸的荧光与剂量率无关。含偏苯三酸的探测器能够在0.6 Gy/min及以上的剂量率下独立于剂量率量化电离辐射的吸收能量,但与均苯四甲酸不同的是,其仅在高达3.8 Gy/min时适用。激发光谱和荧光光谱的稳定性、辐照探测器的褪色、测量结果的可重复性以及两种溶液零值的增加,使得这些剂量计适用于临床常规。

结论

如果进一步的测量能够证明所提出的探测器与辐射类型、辐射质量和温度无关,那么就有一种新的可能性,可以更简单地利用化学剂量计的特定优势。

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