一种新型的水溶性近红外荧光探针，用于特异性监测酪氨酸酶，并应用于小鼠模型。
A novel hydrosoluble near-infrared fluorescent probe for specifically monitoring tyrosinase and application in a mouse model.
机构信息
Shaanxi Engineering Laboratory for Food Green Processing and Safety Control, College of Food Engineering and Nutritional Science, Shaanxi Normal University, Xi'an 710062, China.
出版信息
Chem Commun (Camb). 2019 Aug 7;55(64):9463-9466. doi: 10.1039/c9cc04714j.
PMID:31328200
Abstract
A novel hydrosoluble near-infrared (NIR) fluorescent probe that could specifically identify tyrosinase has been successfully constructed and applied for imaging of tyrosinase in living cells and zebrafish. Notably, the probe has been successfully applied to the diagnosis of melanoma in a xenogeneic mouse model.
摘要
一种新型的水溶性近红外（NIR）荧光探针，可特异性识别酪氨酸酶，已成功构建并应用于活细胞和斑马鱼中酪氨酸酶的成像。值得注意的是，该探针已成功应用于异种移植小鼠模型中黑色素瘤的诊断。
Zotero 插件