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离体条件下评估植物作为离体牙储存介质的效果:一项系统性综述。

In vitro evaluation of plants as storage media for avulsed teeth: A systematic review.

机构信息

Faculty of Dentistry, University of Rio Verde, Rio Verde, Brazil.

Department of Pediatric Dentistry and Integrated Clinic of Faculty of Dentistry, University of Rio Verde, Rio Verde, Brazil.

出版信息

Dent Traumatol. 2020 Feb;36(1):3-18. doi: 10.1111/edt.12501. Epub 2019 Aug 19.

DOI:10.1111/edt.12501
PMID:31328384
Abstract

BACKGROUND/AIMS: Dental avulsion is defined as the complete displacement of a tooth from its socket owing to trauma. The treatment outcome depends on storage of the avulsed teeth in media capable of maintaining the viability of periodontal ligament cells, when immediate replantation is not possible. To maintain the viability of periodontal ligament cells, plants can be used as a storage medium because of their pharmacological and phytotherapic properties. The aim of this study was to evaluate the effect of plants on the tissue repair following tooth replantation.

METHODS

This systematic review was conducted according to the PRISMA guidelines and included articles collected in the Cochrane, LILACS, PubMed, Science Direct, Scopus and Web of Science databases, plus articles found in the grey literature. The articles were screened for partial reading using the Endnote and Rayyan platform. The methodology of studies was evaluated by using the OHAT and GRADE.

RESULTS

In the initial search, 2361 articles were obtained, only 51 articles were submitted to complete reading, and 35 articles were selected for the qualitative analysis. The evaluated plants had a potential effect on cell viability and proliferation. The articles evaluated mainly the action of plants on cells of the periodontal ligament. Propolis, coconut water and Aloe vera were the most common storage medium.

CONCLUSION

The methodological limitations persist, and the evaluation of the pharmacological potential of plants on dental tissues still requires more research.

摘要

背景/目的:牙脱位是指由于创伤导致牙齿完全从牙槽窝中脱出。治疗效果取决于在无法立即进行再植的情况下,将脱位的牙齿储存在能够维持牙周膜细胞活力的介质中。为了保持牙周膜细胞的活力,可以使用植物作为储存介质,因为它们具有药理学和植物疗法特性。本研究旨在评估植物对牙再植后组织修复的影响。

方法

本系统评价按照 PRISMA 指南进行,纳入了 Cochrane、LILACS、PubMed、Science Direct、Scopus 和 Web of Science 数据库中以及灰色文献中收集的文章。使用 Endnote 和 Rayyan 平台对文章进行了初步阅读筛选。使用 OHAT 和 GRADE 评估了研究方法。

结果

在最初的搜索中,获得了 2361 篇文章,只有 51 篇文章提交进行完整阅读,选择了 35 篇文章进行定性分析。评估的植物对细胞活力和增殖具有潜在影响。评估的文章主要关注植物对牙周膜细胞的作用。蜂胶、椰子水和芦荟是最常见的储存介质。

结论

方法学限制仍然存在,植物对牙齿组织的药理学潜力的评估仍需要更多的研究。

相似文献

1
In vitro evaluation of plants as storage media for avulsed teeth: A systematic review.离体条件下评估植物作为离体牙储存介质的效果:一项系统性综述。
Dent Traumatol. 2020 Feb;36(1):3-18. doi: 10.1111/edt.12501. Epub 2019 Aug 19.
2
Evaluation of periodontal ligament cell viability in different storage media based on human PDL cell culture experiments-A systematic review.基于人牙周膜细胞培养实验评估不同储存介质中牙周膜细胞的活力——一项系统评价
Dent Traumatol. 2018 Dec;34(6):384-393. doi: 10.1111/edt.12437. Epub 2018 Oct 21.
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Which is the most recommended medium for the storage and transport of avulsed teeth? A systematic review.对于脱位牙的储存和运输,哪种介质是最推荐的?一项系统评价。
Dent Traumatol. 2018 Apr;34(2):59-70. doi: 10.1111/edt.12382. Epub 2018 Feb 6.
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Avulsion and storage media.撕脱伤与储存介质
J Investig Clin Dent. 2011 May;2(2):89-94. doi: 10.1111/j.2041-1626.2010.00043.x. Epub 2011 Jan 5.
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Storage media for avulsed teeth: a literature review.脱位牙的储存介质:文献综述
Braz Dent J. 2013 Sep-Oct;24(5):437-45. doi: 10.1590/0103-6440201302297.
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An evaluation of efficacy of ViaSpan, gatorade solution, and propolis storage media for maintaining the periodontal ligament cell viability.评价 ViaSpan、佳得乐溶液和蜂胶储存介质维持牙周膜细胞活力的效果。
Ann Afr Med. 2022 Jan-Mar;21(1):34-38. doi: 10.4103/aam.aam_71_20.
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Storage of an avulsed tooth prior to replantation: A systematic review and meta-analysis.脱位牙再植前的储存:系统评价和荟萃分析。
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Study of the effectiveness of propolis extract as a storage medium for avulsed teeth.蜂胶提取物作为离体牙储存介质的效果研究。
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Effect of temperature and seven storage media on human periodontal ligament fibroblast viability.温度和七种储存介质对人牙周膜成纤维细胞活力的影响
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引用本文的文献

1
[Heterotopic replantation and delayed implant restoration following complete avulsion of maxillary central incisors: a case report].[上颌中切牙完全脱位后的异位再植与延期种植修复:1例病例报告]
Hua Xi Kou Qiang Yi Xue Za Zhi. 2025 Aug 1;43(4):534-540. doi: 10.7518/hxkq.2025.2024395.
2
Analysis of the Cytoprotective Effect of . Fruits as a Means of Transporting the Avulsed Teeth.作为运送脱位牙手段的水果的细胞保护作用分析
Int J Dent. 2025 Apr 22;2025:6661398. doi: 10.1155/ijod/6661398. eCollection 2025.