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离体条件下评估植物作为离体牙储存介质的效果:一项系统性综述。

In vitro evaluation of plants as storage media for avulsed teeth: A systematic review.

机构信息

Faculty of Dentistry, University of Rio Verde, Rio Verde, Brazil.

Department of Pediatric Dentistry and Integrated Clinic of Faculty of Dentistry, University of Rio Verde, Rio Verde, Brazil.

出版信息

Dent Traumatol. 2020 Feb;36(1):3-18. doi: 10.1111/edt.12501. Epub 2019 Aug 19.

Abstract

BACKGROUND/AIMS: Dental avulsion is defined as the complete displacement of a tooth from its socket owing to trauma. The treatment outcome depends on storage of the avulsed teeth in media capable of maintaining the viability of periodontal ligament cells, when immediate replantation is not possible. To maintain the viability of periodontal ligament cells, plants can be used as a storage medium because of their pharmacological and phytotherapic properties. The aim of this study was to evaluate the effect of plants on the tissue repair following tooth replantation.

METHODS

This systematic review was conducted according to the PRISMA guidelines and included articles collected in the Cochrane, LILACS, PubMed, Science Direct, Scopus and Web of Science databases, plus articles found in the grey literature. The articles were screened for partial reading using the Endnote and Rayyan platform. The methodology of studies was evaluated by using the OHAT and GRADE.

RESULTS

In the initial search, 2361 articles were obtained, only 51 articles were submitted to complete reading, and 35 articles were selected for the qualitative analysis. The evaluated plants had a potential effect on cell viability and proliferation. The articles evaluated mainly the action of plants on cells of the periodontal ligament. Propolis, coconut water and Aloe vera were the most common storage medium.

CONCLUSION

The methodological limitations persist, and the evaluation of the pharmacological potential of plants on dental tissues still requires more research.

摘要

背景/目的:牙脱位是指由于创伤导致牙齿完全从牙槽窝中脱出。治疗效果取决于在无法立即进行再植的情况下,将脱位的牙齿储存在能够维持牙周膜细胞活力的介质中。为了保持牙周膜细胞的活力,可以使用植物作为储存介质,因为它们具有药理学和植物疗法特性。本研究旨在评估植物对牙再植后组织修复的影响。

方法

本系统评价按照 PRISMA 指南进行,纳入了 Cochrane、LILACS、PubMed、Science Direct、Scopus 和 Web of Science 数据库中以及灰色文献中收集的文章。使用 Endnote 和 Rayyan 平台对文章进行了初步阅读筛选。使用 OHAT 和 GRADE 评估了研究方法。

结果

在最初的搜索中,获得了 2361 篇文章,只有 51 篇文章提交进行完整阅读,选择了 35 篇文章进行定性分析。评估的植物对细胞活力和增殖具有潜在影响。评估的文章主要关注植物对牙周膜细胞的作用。蜂胶、椰子水和芦荟是最常见的储存介质。

结论

方法学限制仍然存在,植物对牙齿组织的药理学潜力的评估仍需要更多的研究。

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