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[重复局部刺激期间皮质神经元微系统中的可塑性及其生理标记物]

[Plasticity and its physiological markers in the microsystem of cortical neurons during repeated local stimulation].

作者信息

Kotliar B I, Miasnikov A A, Khludova G G

出版信息

Nauchnye Doki Vyss Shkoly Biol Nauki. 1988(3):93-111.

PMID:3132987
Abstract

Separate neuronal microsystems in the sensomotor cerebral cortex are able to exhibit the functional plasticity under conditions of repeated action of acetylcholine applied microiontophoretically. The characteristic properties of dynamics in activity of single cortex neurones are determined mainly by the initial reactivity to transmitter and by the state of nervous cells of the surrounding microsystem. The composition and succession of response components as well the duration of excitatory stage of reaction to acetylcholine serve as physiological markers of plastic properties of neurones in cortical microsystem.

摘要

感觉运动性大脑皮层中不同的神经元微系统,在微离子电泳施加乙酰胆碱的重复作用条件下,能够表现出功能可塑性。单个皮层神经元活动的动力学特征特性,主要由对递质的初始反应性以及周围微系统神经细胞的状态所决定。反应成分的组成和顺序以及对乙酰胆碱反应的兴奋期持续时间,可作为皮层微系统中神经元可塑性特性的生理标志。

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