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有症状的或动脉瘤样异常锁骨下动脉:手术和杂交修复的结果

Symptomatic or aneurysmal aberrant subclavian arteries: results of surgical and hybrid repair.

作者信息

Weiss Salome, Haligür Didem, Jungi Silvan, Schönhoff Florian S, Carrel Thierry, Schmidli Jürg, Wyss Thomas R

机构信息

Department of Cardiovascular Surgery, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.

出版信息

Interact Cardiovasc Thorac Surg. 2019 Sep 1;29(3):344-351. doi: 10.1093/icvts/ivz095.

Abstract

OBJECTIVES

Indications and techniques of repair for symptomatic or aneurysmal aberrant subclavian arteries (ASA) are controversial. This study analyses presentation, treatment and outcome of patients with symptomatic and/or aneurysmal ASA.

METHODS

Retrospective analysis of consecutive adult patients undergoing symptomatic and/or aneurysmal ASA repair between January 2000 and June 2016.

RESULTS

Of 12 patients (4 females) with a median age of 66 years (range 24-75), 10 had right ASA and 2 had left ASA originating from a right aortic arch. Six patients (50%) had Kommerell's diverticulum and 6 patients had aneurysmal dilatation of the ASA itself. Six patients presented with symptoms (dysphagia n = 4, chest pain n = 1, recurrent aspiration n = 1). Nine patients (75%) were treated by open ASA resection/ligation with or without aortic repair. Three patients (25%) underwent hybrid repair using thoracic endovascular aortic repair to exclude the aberrant artery. ASA revascularization was achieved by subclavian-carotid transposition (n = 7), carotid-subclavian bypass (n = 1), aorto-subclavian bypass (n = 3) or reimplantation after aortic graft replacement (n = 1). Thirty-day mortality was 8% (n = 1). The median follow-up duration was 44 months (range 24-151). Symptoms were relieved in 4 and persisted partially in 1, while symptom relief remained unknown in 1 patient who died during follow-up. Imaging after a median of 34 months (range 2-134) after the operation showed patent ASA revascularization in all patients and no endoleaks in the hybrid group.

CONCLUSIONS

Surgical and hybrid repair allows satisfying results in patients with symptomatic and/or aneurysmal ASA. The optimal procedure has to be defined on an individual patient basis. Further studies, preferably with a multicentre approach, are required to answer more specific questions on the management of these patients and especially to assess long-term results following hybrid repair.

摘要

目的

有症状的或动脉瘤样异常锁骨下动脉(ASA)的修复指征和技术存在争议。本研究分析有症状的和/或动脉瘤样ASA患者的临床表现、治疗及预后。

方法

对2000年1月至2016年6月期间连续接受有症状的和/或动脉瘤样ASA修复的成年患者进行回顾性分析。

结果

12例患者(4例女性),中位年龄66岁(范围24 - 75岁),10例为右侧ASA,2例为起源于右主动脉弓的左侧ASA。6例患者(50%)有Kommerell憩室,6例患者ASA本身存在动脉瘤样扩张。6例患者出现症状(吞咽困难4例,胸痛1例,反复误吸1例)。9例患者(75%)接受了开放的ASA切除/结扎术,伴或不伴主动脉修复。3例患者(25%)接受了杂交修复,采用胸段血管腔内主动脉修复术以隔绝异常动脉。通过锁骨下 - 颈动脉转位(7例)、颈动脉 - 锁骨下旁路移植术(1例)、主动脉 - 锁骨下旁路移植术(3例)或主动脉移植置换术后再植入术(1例)实现了ASA血运重建。30天死亡率为8%(1例)。中位随访时间为44个月(范围24 - 151个月)。4例患者症状缓解,1例部分缓解,1例在随访期间死亡,其症状缓解情况未知。术后中位34个月(范围2 - 134个月)的影像学检查显示所有患者的ASA血运重建通畅,杂交组无内漏。

结论

手术和杂交修复对于有症状的和/或动脉瘤样ASA患者可取得满意结果。最佳手术方式必须根据个体患者情况确定。需要进一步研究,最好采用多中心方法,以回答关于这些患者管理的更具体问题,尤其是评估杂交修复后的长期结果。

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