Division of Hematology/Oncology, McMaster Children's Hospital at Hamilton Health Sciences, Hamilton, Ontario, Canada.
Division of Hematology/Oncology, Ann and Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Pediatr Blood Cancer. 2019 Sep;66(9):e27827. doi: 10.1002/pbc.27827. Epub 2019 Jun 10.
Chronic myeloid leukemia (CML) accounts for 2-3% of leukemias in children under 15 and 9% in adolescents aged 15-19. The diagnosis and management of CML in children, adolescents, and young adults have several differences compared to that in adults. This review outlines the diagnosis and management of the underlying disease as well as challenges that can occur when dealing with CML in this patient population.
儿童慢性髓性白血病（CML）占 15 岁以下儿童白血病的 2-3%，占 15-19 岁青少年白血病的 9%。儿童、青少年和年轻成人 CML 的诊断和管理与成人有许多不同。本文概述了基础疾病的诊断和管理，以及在该患者人群中治疗 CML 时可能出现的挑战。
