Sato O, Maeda T, Kobayashi S, Iwanaga T, Fujita T
Department of Oral Anatomy, Niigata University School of Dentistry, Japan.
Cell Tissue Res. 1988 May;252(2):231-8. doi: 10.1007/BF00214365.
Nervous elements supplying the filiform papillae of the tongue of cattle and rats were investigated using immunohistochemistry against neurofilament protein (NFP) and glia-specific S-100 protein. The rod-shaped bovine filiform papillae were heavily keratinized along their entire length and lacked the connective tissue core that occurs in other mammals. Instead, the core was located posterior to the filiform papilla. The base of the bovine filiform papillae was invaded vertically by laminar connective tissue papillae. The core contained a large number of NFP-positive nerve fibers, most of them terminating as free endings in its anterior margin. NFP-positive nerves gathered around the anterior ridge of the epithelium at the base of the core and occasionally penetrated into the epithelium. The laminar connective tissue papillae at the base of the filiform papilla also contained NFP-positive nerve fibers. The core contained S-100-immunoreactive lamellated corpuscles, which were identified as "simple corpuscles" in electron micrographs. The structure and innervation of the bovine filiform papilla suggest that they represent a specialized sensory apparatus. The pyramidal filiform papillae of the rat were smaller, each containing a simple connective tissue core. Few NFP-positive nerve fibers from the nerve plexus entered the core. Filiform papillae are thus less specialized in rats than in cattle.
利用抗神经丝蛋白（NFP）和胶质细胞特异性S-100蛋白的免疫组织化学方法，对供应牛和大鼠舌丝状乳头的神经成分进行了研究。棒状的牛丝状乳头在其整个长度上都高度角化，并且缺乏其他哺乳动物中存在的结缔组织核心。相反，该核心位于丝状乳头的后方。牛丝状乳头的基部被层状结缔组织乳头垂直侵入。核心包含大量NFP阳性神经纤维，其中大多数以前缘的游离末梢形式终止。NFP阳性神经聚集在核心基部上皮的前缘周围，偶尔穿透上皮。丝状乳头基部的层状结缔组织乳头也含有NFP阳性神经纤维。核心包含S-100免疫反应性环层小体，在电子显微镜照片中被鉴定为“简单小体”。牛丝状乳头的结构和神经支配表明它们代表一种特殊的感觉器官。大鼠的锥形丝状乳头较小，每个都含有一个简单的结缔组织核心。来自神经丛的NFP阳性神经纤维很少进入核心。因此，丝状乳头在大鼠中比在牛中专业化程度更低。
