Advanced Eye Center, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
Indian J Ophthalmol. 2019 Aug;67(8):1368-1371. doi: 10.4103/ijo.IJO_2077_18.
A 48-year-old female presented with complaints of recent onset diminution of vision of the left eye (OS) for the past 2 months. She was highly myopic and was using glasses for the past 30 years. Ocular examination revealed presence of a myopic fundus with high axial lengths in both the eyes. Fundus examination of the OS revealed a myopic tessellated fundus with prominent choroidal vessels and a blunted foveal reflex. There was a small pale whitish lesion just superior to the foveal center. Optical coherence tomography (OCT) scans (both horizontal and vertical) confirmed presence of dome-shaped maculopathy. There was subretinal fluid in the OS. A vertical OCT scan also revealed a subretinal hyperreflective material, which was confirmed to be due to a small mixed type 1 and type 2 choroidal neovascularization (CNV) on swept-source (SS) OCT angiography in the OS. The patient was given intravitreal injection of ranibizumab (0.5 mg/0.05 mL) in the OS. At 1-month follow-up, the subretinal fluid completely resolved. The CNV lesion regressed significantly on SS-OCT angiography. The best-corrected visual acuity improved from 20/80 to 20/20 in the OS, which was maintained at 3 months of follow-up.
一位 48 岁女性因左眼（OS）视力减退 2 个月前来就诊。她高度近视，过去 30 年来一直戴着眼镜。眼部检查显示双眼存在高度轴性近视性眼底。OS 的眼底检查显示近视性棋盘格眼底，脉络膜血管明显，中心凹反射变钝。在中心凹上方有一个小的苍白白色病变。光学相干断层扫描（OCT）扫描（水平和垂直）证实存在盘状黄斑病变。OS 存在视网膜下积液。垂直 OCT 扫描还显示视网膜下高反射物质，在 OS 的扫频源（SS）OCT 血管造影上证实为小的混合型 1 型和 2 型脉络膜新生血管（CNV）。在 OS 中给予雷珠单抗（0.5mg/0.05ml）玻璃体腔内注射。1 个月随访时，视网膜下液完全吸收。SS-OCT 血管造影显示 CNV 病变明显消退。OS 的最佳矫正视力从 20/80 提高到 20/20，在 3 个月的随访中保持稳定。
