文献综述及预防和治疗角膜移植排斥反应的建议方案。
Literature review and suggested protocol for prevention and treatment of corneal graft rejection.
机构信息
Porto Alegre Eye Bank Hospital, Porto Alegre, Brazil.
Sussex Eye Hospital, Brighton, England.
出版信息
Eye (Lond). 2020 Mar;34(3):442-450. doi: 10.1038/s41433-019-0517-9. Epub 2019 Jul 22.
Abstract
Effective prophylaxis and treatment of corneal graft rejection are essential to improve outcomes in corneal transplantation. To date, there has been no standardized protocol published that outlines the optimal prophylactic and therapeutic approaches and, furthermore, the published controlled trials on this subject are limited. Likewise, no study has addressed how the level of antigen exposure varies between different types of keratoplasties. The aim of this paper is to provide a simple evidence-based protocol for the prevention and treatment of corneal graft rejection.
摘要
有效的角膜移植排斥反应预防和治疗对于改善角膜移植的结果至关重要。迄今为止，尚无发表的标准化方案来概述最佳的预防和治疗方法，而且该主题的已发表对照试验也很有限。同样，也没有研究探讨不同类型的角膜移植之间抗原暴露水平的差异。本文旨在提供一种简单的基于证据的角膜移植排斥反应预防和治疗方案。
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