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Hypothermic oxygenated machine perfusion-Preliminary experience with end-ischemic reconditioning of marginal kidney allografts.

作者信息

Meister Franziska Alexandra, Czigany Zoltan, Bednarsch Jan, Boecker Joerg, Wiltberger Georg, Rohlfs Wilko, Neumann Ulf Peter, Lurje Georg

机构信息

Department of Surgery and Transplantation, University Hospital RWTH Aachen, Aachen, Germany.

Institute of Heat and Mass Transfer, RWTH Aachen University, Aachen, Germany.

出版信息

Clin Transplant. 2019 Oct;33(10):e13673. doi: 10.1111/ctr.13673. Epub 2019 Aug 7.

DOI:10.1111/ctr.13673
PMID:31332838
Abstract
摘要

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Hypothermic oxygenated machine perfusion-Preliminary experience with end-ischemic reconditioning of marginal kidney allografts.低温氧合机器灌注——边缘性同种异体肾移植缺血后处理的初步经验
Clin Transplant. 2019 Oct;33(10):e13673. doi: 10.1111/ctr.13673. Epub 2019 Aug 7.
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Does machine perfusion decrease ischemia reperfusion injury?机器灌注能减少缺血再灌注损伤吗？
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One or 4 h of "in-house" reconditioning by machine perfusion after cold storage improve reperfusion parameters in porcine kidneys.冷藏后通过机器灌注进行1或4小时的“内部”修复可改善猪肾的再灌注参数。
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Impact of static cold storage VS hypothermic machine preservation on ischemic kidney graft: inflammatory cytokines and adhesion molecules as markers of ischemia/reperfusion tissue damage. Our preliminary results.静态冷藏与低温机器保存对缺血性肾移植物的影响：作为缺血/再灌注组织损伤标志物的炎症细胞因子和黏附分子。我们的初步结果。
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Oxygenated kidney preservation techniques.氧合肾脏保存技术。
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Reconditioning by end-ischemic hypothermic in-house machine perfusion: A promising strategy to improve outcome in expanded criteria donors kidney transplantation.采用终末期缺血性低温自体机器灌注进行修复：一种改善边缘供肾肾移植结局的有前景的策略。
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Machine perfusion of the liver and in vivo animal models: A systematic review of the preclinical research landscape.肝脏的机械灌注和体内动物模型：临床前研究领域的系统综述。
PLoS One. 2024 Feb 8;19(2):e0297942. doi: 10.1371/journal.pone.0297942. eCollection 2024.
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Intermittent Surface Oxygenation Results in Similar Mitochondrial Protection and Maintenance of Aerobic Metabolism as Compared to Continuous Oxygenation during Hypothermic Machine Kidney Machine Perfusion.与低温机器肾灌注期间持续氧合相比，间歇性表面氧合可产生相似的线粒体保护作用并维持有氧代谢。
J Clin Med. 2023 May 29;12(11):3731. doi: 10.3390/jcm12113731.
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Current Evidence and Future Perspectives to Implement Continuous and End-Ischemic Use of Normothermic and Oxygenated Hypothermic Machine Perfusion in Clinical Practice.
在临床实践中实施常温及氧合低温机器灌注持续和缺血末期使用的当前证据及未来展望。
J Clin Med. 2023 Apr 29;12(9):3207. doi: 10.3390/jcm12093207.
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New Frontiers in Organ Preservation and Hepatoprotection.器官保存与肝保护的新前沿。
Int J Mol Sci. 2022 Apr 15;23(8):4379. doi: 10.3390/ijms23084379.
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Simply Adding Oxygen during Hypothermic Machine Perfusion to Combat the Negative Effects of Ischemia-Reperfusion Injury: Fundamentals and Current Evidence for Kidneys.在低温机器灌注期间简单添加氧气以对抗缺血再灌注损伤的负面影响：肾脏的基础与当前证据
Biomedicines. 2021 Aug 11;9(8):993. doi: 10.3390/biomedicines9080993.
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Adenosine A2a Receptor Stimulation Attenuates Ischemia-Reperfusion Injury and Improves Survival in A Porcine Model of DCD Liver Transplantation.腺苷 A2a 受体刺激可减轻缺血再灌注损伤并提高 DCD 肝移植猪模型的存活率。
Int J Mol Sci. 2020 Sep 14;21(18):6747. doi: 10.3390/ijms21186747.