铟-111自体混合白细胞扫描能否准确评估克罗恩病的病变范围及活动度？
Can 111indium autologous mixed leucocyte scanning accurately assess disease extent and activity in Crohn's disease?
作者信息
Park R H, McKillop J H, Duncan A, MacKenzie J F, Russell R I
机构信息
Gastroenterology Unit, Royal Infirmary, Glasgow.
出版信息
Gut. 1988 Jun;29(6):821-5. doi: 10.1136/gut.29.6.821.
Abstract
111Indium autologous mixed leucocyte scanning has recently been used for the investigation of Crohn's disease. Nineteen patients had indium scans to assess disease extent and activity. The scans were compared with conventional imaging techniques and indices of disease activity including clinical scores, ESR, CRP, and GI protein loss. In five patients with active disease the scans were negative and overall there was poor correlation between the scan scores and the other indices of disease activity. Indium scanning correctly located extent of disease in only 58% of patients. 111Indium mixed leucocyte scanning may be more suited for the assessment of disease extent and activity in severely ill patients with Crohn's disease.
摘要
铟 - 111自体混合白细胞扫描最近已被用于克罗恩病的研究。19名患者接受了铟扫描以评估疾病范围和活动程度。这些扫描结果与传统成像技术以及疾病活动指标进行了比较，这些指标包括临床评分、血沉（ESR）、C反应蛋白（CRP）和胃肠道蛋白丢失。在5名患有活动性疾病的患者中，扫描结果为阴性，总体而言，扫描评分与其他疾病活动指标之间的相关性较差。铟扫描仅在58%的患者中正确定位了疾病范围。铟 - 111混合白细胞扫描可能更适合评估患有克罗恩病的重症患者的疾病范围和活动程度。
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