Logan R F, Gillon J, Ferrington C, Ferguson A
Gut. 1981 May;22(5):383-7. doi: 10.1136/gut.22.5.383.
Seven patients with hypoalbuminaemia and extensive jejunoileal Crohn's disease were treated with an elemental diet for 28 to 56 days. Over this time there was an increase in total plasma proteins from mean of 49.1 to 59.0 g/l and a mean rise in serum albumin from 20.7 to 30.0 g/l (P less than 0.05). In addition, there was a 47% mean reduction in plasma protein loss into the gastrointestinal tract and a rise in blood lymphocyte count in all patients (P less than 0.05). These results suggests that, as well as providing nutritional support, elemental diets reduce protein and lymphocyte loss from the diseased intestine.
七名患有低白蛋白血症和广泛空回肠克罗恩病的患者接受了要素饮食治疗,为期28至56天。在此期间,血浆总蛋白从平均49.1克/升增加到59.0克/升,血清白蛋白平均从20.7克/升升至30.0克/升(P小于0.05)。此外,所有患者胃肠道血浆蛋白丢失平均减少47%,血淋巴细胞计数上升(P小于0.05)。这些结果表明,要素饮食除了提供营养支持外,还能减少病变肠道的蛋白质和淋巴细胞丢失。