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要素饮食减少小肠克罗恩病患者胃肠道蛋白质丢失

Reduction of gastrointestinal protein loss by elemental diet in Crohn's disease of the small bowel.

作者信息

Logan R F, Gillon J, Ferrington C, Ferguson A

出版信息

Gut. 1981 May;22(5):383-7. doi: 10.1136/gut.22.5.383.

DOI:10.1136/gut.22.5.383
PMID:7250750
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1419253/
Abstract

Seven patients with hypoalbuminaemia and extensive jejunoileal Crohn's disease were treated with an elemental diet for 28 to 56 days. Over this time there was an increase in total plasma proteins from mean of 49.1 to 59.0 g/l and a mean rise in serum albumin from 20.7 to 30.0 g/l (P less than 0.05). In addition, there was a 47% mean reduction in plasma protein loss into the gastrointestinal tract and a rise in blood lymphocyte count in all patients (P less than 0.05). These results suggests that, as well as providing nutritional support, elemental diets reduce protein and lymphocyte loss from the diseased intestine.

摘要

七名患有低白蛋白血症和广泛空回肠克罗恩病的患者接受了要素饮食治疗,为期28至56天。在此期间,血浆总蛋白从平均49.1克/升增加到59.0克/升,血清白蛋白平均从20.7克/升升至30.0克/升(P小于0.05)。此外,所有患者胃肠道血浆蛋白丢失平均减少47%,血淋巴细胞计数上升(P小于0.05)。这些结果表明,要素饮食除了提供营养支持外,还能减少病变肠道的蛋白质和淋巴细胞丢失。

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Reduction of gastrointestinal protein loss by elemental diet in Crohn's disease of the small bowel.要素饮食减少小肠克罗恩病患者胃肠道蛋白质丢失
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引用本文的文献

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Nutritional Therapy Strategies in Pediatric Crohn's Disease.儿科克罗恩病的营养治疗策略。
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Enteral nutrition in Crohn's disease: an underused therapy.克罗恩病的肠内营养:一种未得到充分利用的治疗方法。
Gastroenterol Res Pract. 2013;2013:482108. doi: 10.1155/2013/482108. Epub 2013 Dec 5.
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Nutritional management of Crohn's disease.克罗恩病的营养管理。
Therap Adv Gastroenterol. 2013 May;6(3):231-42. doi: 10.1177/1756283X13477715.
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Supplementary enteral nutrition maintains remission in paediatric Crohn's disease.补充肠内营养可维持小儿克罗恩病的缓解。
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Initial response and subsequent course of Crohn's disease treated with elemental diet or prednisolone.采用要素饮食或泼尼松龙治疗克罗恩病的初始反应及后续病程
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Immunological functions of the gut in relation to nutritional state and mode of delivery of nutrients.肠道的免疫功能与营养状态及营养物质输送方式的关系。
Gut. 1994 Jan;35(1 Suppl):S10-2. doi: 10.1136/gut.35.1_suppl.s10.
7
Controlled trial of oligopeptide versus amino acid diet in treatment of active Crohn's disease.
Gut. 1995 Jan;36(1):60-6. doi: 10.1136/gut.36.1.60.
8
Intense nutritional support in inflammatory bowel disease.炎症性肠病的强化营养支持
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Elemental diet in acute Crohn's disease.急性克罗恩病中的要素饮食
Arch Dis Child. 1983 Jan;58(1):44-7. doi: 10.1136/adc.58.1.44.
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Crohn's disease treated by elemental diet.要素饮食治疗克罗恩病。
J R Soc Med. 1982 Feb;75(2):135-6.

本文引用的文献

1
Exudative enteropathy. I. A comparative study of Cr51-Cl and I-131-PVP.渗出性肠病。I. 铬51-氯和碘131-聚乙烯吡咯烷酮的比较研究。
J Lab Clin Med. 1961 Dec;58:892-901.
2
Demonstration of protein-losing gastroenteropathy. The quantitative estimation of gastrointestinal protein loss, using 51Cr-labelled plasma proteins.
Clin Chim Acta. 1966 Jul;14(1):42-8. doi: 10.1016/0009-8981(66)90062-3.
3
Use of concentrated, balanced, liquid elemental diet for nutritional management of catabolic states.使用浓缩、均衡的液体元素饮食对分解代谢状态进行营养管理。
Ann Surg. 1969 Oct;170(4):642-68. doi: 10.1097/00000658-196910000-00015.
4
The role of the gastrointestinal tract in plasma protein metabolism. Studies with 51Cr-albumin.胃肠道在血浆蛋白代谢中的作用。用51铬标记白蛋白的研究。
Am J Med. 1969 Feb;46(2):275-85. doi: 10.1016/0002-9343(69)90011-4.
5
Intestinal protein loss in Crohn's disease.克罗恩病中的肠道蛋白质丢失
Gastroenterology. 1972 Feb;62(2):207-15.
6
Protein-losing enteropathy and kinetic studies of plasma protein metabolism.蛋白丢失性肠病与血浆蛋白代谢动力学研究
Semin Nucl Med. 1972 Jul;2(3):251-63. doi: 10.1016/s0001-2998(72)80036-9.
7
Use of chemically defined diets in the management of patients with acute inflammatory bowel disease.化学限定饮食在急性炎症性肠病患者管理中的应用。
Am J Surg. 1974 Apr;127(4):469-75. doi: 10.1016/0002-9610(74)90299-2.
8
Experience with elemental diet in the treatment of inflammatory bowel disease. Is this primary therapy?
Arch Surg. 1973 Aug;107(2):329-33. doi: 10.1001/archsurg.1973.01350200189039.
9
Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study.克罗恩病活动指数的制定。全国克罗恩病合作研究。
Gastroenterology. 1976 Mar;70(3):439-44.
10
Assessment of the therapeutic value of an elemental diet in chronic inflammatory bowel disease.
Scand J Gastroenterol. 1977;12(1):89-95.