Razavi Seyed Esmail, Farhangmehr Vahid, Babaie Zahra
Department of Mechanical Engineering, University of Tabriz, Tabriz, Iran.
Department of Mechanical Engineering, University of Bonab, Bonab 5551761167, Iran.
Bioimpacts. 2019;9(2):97-103. doi: 10.15171/bi.2019.13. Epub 2019 Mar 8.
The effect of a bare-metal stent on the hemodynamics in the main branch of a coronary artery bifurcation with a particular type of stenosis was numerically investigated by the computational fluid dynamics (CFD). Three-dimensional idealized geometry of bifurcation was constructed in Catia modelling commercial software package. The Newtonian blood flow was assumed to be incompressible and laminar. CFD was utilized to calculate the shear stress and blood pressure distributions on the wall of main branch. In order to do the numerical simulations, a commercial software package named as COMSOL Multiphysics 5.3 was employed. Two types of stent , namely, one-part stent and two-part stent were applied to prevent the build-up and progression of the atherosclerotic plaques in the main branch. A particular type of stenosis in the main branch was considered in this research. It occurred before and after the side branch. Moreover, it was found that the main branch with an inserted one-part stent had the smallest region with the wall shear stress (WSS) below 0.5 Pa which was the minimum WSS in the main branch without the stenosis. The use of a one-part stent in the main branch of a coronary artery bifurcation for the aforementioned type of stenosis is recommended.
通过计算流体动力学（CFD）对裸金属支架对具有特定类型狭窄的冠状动脉分叉主支血流动力学的影响进行了数值研究。在Catia建模商业软件包中构建了三维理想化分叉几何模型。假设牛顿血流是不可压缩的且为层流。利用CFD计算主支壁上的剪应力和血压分布。为进行数值模拟，采用了名为COMSOL Multiphysics 5.3的商业软件包。应用了两种类型的支架，即一体式支架和分体式支架，以防止主支中动脉粥样硬化斑块的形成和进展。本研究考虑了主支中一种特定类型的狭窄。它发生在侧支之前和之后。此外，发现插入一体式支架的主支具有壁面剪应力（WSS）低于0.5 Pa的最小区域，这是无狭窄主支中的最小WSS。建议对上述类型的狭窄在冠状动脉分叉主支中使用一体式支架。
