Sonthalia Sidharth, Agrawal Mahima, Sehgal V N
Department of Dermatology and Dermatosurgery, Skinnocence, The Skin Clinic and Research Centre, Gurugram, Haryana, India.
Department of Dermatology and STD, LHMC and Associated Hospitals, Panchwati-Delhi, India.
Indian Dermatol Online J. 2019 Jul-Aug;10(4):481-485. doi: 10.4103/idoj.IDOJ_29_19.
The injudicious use of antifungals, indiscriminate use of corticosteroids for instant relief, persistence of predisposing factors like sweat retention and uncontrolled diabetes, and emerging resistance to antifungals across the globe have rendered the management of an erstwhile simple infection, the superficial cutaneous mycoses highly complicated and tricky. Ciclopirox is an old yet efficacious, versatile, and safe topical antifungal of the hydroxypyridone family. Despite its numerous beneficial properties over the majority of other topical antifungals, it remains underutilized.
抗真菌药物的不当使用、为迅速缓解症状而不加区分地使用皮质类固醇、诸如汗液潴留和糖尿病控制不佳等易感因素的持续存在,以及全球范围内对抗真菌药物出现的耐药性,使得曾经简单的浅表皮肤真菌感染的治疗变得高度复杂和棘手。环吡酮是一种古老但有效、多功能且安全的羟基吡啶酮类外用抗真菌药。尽管它相对于大多数其他外用抗真菌药具有许多有益特性,但仍未得到充分利用。