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Topical antiviral and antifungal medications in pregnancy: a review of safety profiles.妊娠期局部抗病毒和抗真菌药物:安全性概况综述。
J Eur Acad Dermatol Venereol. 2017 Sep;31(9):1440-1446. doi: 10.1111/jdv.14297. Epub 2017 Aug 4.
2
Topical Treatment of Facial Seborrheic Dermatitis: A Systematic Review.面部脂溢性皮炎的局部治疗:一项系统评价。
Am J Clin Dermatol. 2017 Apr;18(2):193-213. doi: 10.1007/s40257-016-0232-2.
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[Phase III study of the efficacy and safety of ciclopirox olamine cream in small children with dermatomycosis].环吡酮胺乳膏治疗小儿皮肤癣菌病的疗效和安全性Ⅲ期研究
Rev Iberoam Micol. 2015 Jul-Sep;32(3):164-9. doi: 10.1016/j.riam.2014.04.002. Epub 2014 Oct 27.
4
In-vitro Activity of 10 Antifungal Agents against 320 Dermatophyte Strains Using Microdilution Method in Tehran.在德黑兰采用微量稀释法检测10种抗真菌药物对320株皮肤癣菌的体外活性。
Iran J Pharm Res. 2013 Summer;12(3):537-45.
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Ciclopirox: recent nonclinical and clinical data relevant to its use as a topical antimycotic agent.环吡酮胺:作为一种局部抗真菌药物,其近期的非临床和临床数据。
Drugs. 2010 Nov 12;70(16):2133-52. doi: 10.2165/11538110-000000000-00000.
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Topical treatments for fungal infections of the skin and nails of the foot.足部皮肤和指甲真菌感染的局部治疗方法。
Cochrane Database Syst Rev. 2007 Jul 18;2007(3):CD001434. doi: 10.1002/14651858.CD001434.pub2.
7
Clinical efficacies of shampoos containing ciclopirox olamine (1.5%) and ketoconazole (2.0%) in the treatment of seborrhoeic dermatitis.含环吡酮胺(1.5%)和酮康唑(2.0%)洗发水治疗脂溢性皮炎的临床疗效
J Dermatolog Treat. 2007;18(2):88-96. doi: 10.1080/16537150601092944.
8
Clinical efficacy of a new ciclopiroxolamine/zinc pyrithione shampoo in scalp seborrheic dermatitis treatment.一种新型环吡酮胺/吡硫翁锌洗发水治疗头皮脂溢性皮炎的临床疗效
Eur J Dermatol. 2006 Sep-Oct;16(5):558-64.
9
Treatment of head and neck dermatitis with ciclopiroxolamine cream--results of a double-blind, placebo-controlled study.用环吡酮胺乳膏治疗头颈部皮炎——一项双盲、安慰剂对照研究的结果
Skin Pharmacol Physiol. 2006;19(3):153-8. doi: 10.1159/000092596. Epub 2006 Apr 6.
10
Evaluation of the efficacy of ciclopirox 0.77% gel in the treatment of tinea pedis interdigitalis (dermatophytosis complex) in a randomized, double-blind, placebo-controlled trial.在一项随机、双盲、安慰剂对照试验中评估0.77%环吡酮凝胶治疗指间足癣(复合皮肤癣菌病)的疗效。
Int J Dermatol. 2005 Jul;44(7):590-3. doi: 10.1111/j.1365-4632.2004.02559.x.

外用1%环吡酮胺:重新审视一种独特的抗真菌药。

Topical Ciclopirox Olamine 1%: Revisiting a Unique Antifungal.

作者信息

Sonthalia Sidharth, Agrawal Mahima, Sehgal V N

机构信息

Department of Dermatology and Dermatosurgery, Skinnocence, The Skin Clinic and Research Centre, Gurugram, Haryana, India.

Department of Dermatology and STD, LHMC and Associated Hospitals, Panchwati-Delhi, India.

出版信息

Indian Dermatol Online J. 2019 Jul-Aug;10(4):481-485. doi: 10.4103/idoj.IDOJ_29_19.

DOI:10.4103/idoj.IDOJ_29_19
PMID:31334080
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6615394/
Abstract

The injudicious use of antifungals, indiscriminate use of corticosteroids for instant relief, persistence of predisposing factors like sweat retention and uncontrolled diabetes, and emerging resistance to antifungals across the globe have rendered the management of an erstwhile simple infection, the superficial cutaneous mycoses highly complicated and tricky. Ciclopirox is an old yet efficacious, versatile, and safe topical antifungal of the hydroxypyridone family. Despite its numerous beneficial properties over the majority of other topical antifungals, it remains underutilized.

摘要

抗真菌药物的不当使用、为迅速缓解症状而不加区分地使用皮质类固醇、诸如汗液潴留和糖尿病控制不佳等易感因素的持续存在,以及全球范围内对抗真菌药物出现的耐药性,使得曾经简单的浅表皮肤真菌感染的治疗变得高度复杂和棘手。环吡酮是一种古老但有效、多功能且安全的羟基吡啶酮类外用抗真菌药。尽管它相对于大多数其他外用抗真菌药具有许多有益特性,但仍未得到充分利用。