Abdelazim Ibrahim A, Abu-Faza Mohannad, Hamed Mohamed E S, Amer Osama O, Shikanova Svetlana, Zhurabekova Gulmira
Department of Obstetrics and Gynecology, Ain Shams University, Cairo, Egypt.
Department of Obstetrics and Gynecology, Ahmadi Hospital, Kuwait Oil Company, Ahmadi, Kuwait.
J Family Med Prim Care. 2019 Jun;8(6):2151-2154. doi: 10.4103/jfmpc.jfmpc_394_19.
Fetuses with single umbilical artery (SUA) at great risk of intrauterine growth retardation (IUGR), intrauterine fetal death (IUFD) and prematurity. A 24-years-old woman, 28 weeks' gestation, presented to the Ahmadi hospital, Kuwait, with history of preterm premature rupture of fetal membranes (PPROM). After exclusion of the PPROM, the ultrasound scan of the studied woman showed; asymmetrical IUGR with SUA. The diagnosis of SUA confirmed by the color flow Doppler. She delivered spontaneously at 36 weeks+2, and a cut section in the umbilical cord done to confirm the diagnosis of SUA. The congenital and chromosomal abnormalities of the studied neonate excluded after normal pelvi-abdominal, brain ultrasound and normal karyotyping (46, xx); respectively. The prenatal diagnosed SUA in the studied cases associated with IUGR, preterm labor (PTL) and small for gestational age (SGA). SUA can be considered a marker of diagnosable congenital fetal malformation (CFM) and aneuploidy.
单脐动脉（SUA）胎儿发生宫内生长受限（IUGR）、胎儿宫内死亡（IUFD）和早产的风险很高。一名24岁、孕28周的女性因胎膜早破（PPROM）早产史前往科威特艾哈迈迪医院就诊。排除PPROM后，对该女性进行超声检查显示：单脐动脉合并不对称性宫内生长受限。彩色多普勒血流成像确诊为单脐动脉。她于孕36周+2时自然分娩，并对脐带进行了切开检查以确诊单脐动脉。经骨盆腹部、脑部超声检查正常以及染色体核型分析正常（46, XX），排除了所研究新生儿的先天性和染色体异常。在所研究的病例中，产前诊断的单脐动脉与宫内生长受限、早产（PTL）和小于胎龄儿（SGA）有关。单脐动脉可被视为可诊断的先天性胎儿畸形（CFM）和非整倍体的标志物。
