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肿瘤 F-FDG PET/CT 成像中感染和炎症的影响。

The impact of infection and inflammation in oncologic F-FDG PET/CT imaging.

机构信息

Nuclear Medicine Division, Department of Radiology, University of Michigan Hospital, Ann Arbor, MI, USA.

Nuclear Medicine Division, Department of Radiology, University of Michigan Hospital, Ann Arbor, MI, USA; Nuclear Medicine Service, Department of Veterans Affairs Health System, Ann Arbor, MI, USA.

出版信息

Biomed Pharmacother. 2019 Sep;117:109168. doi: 10.1016/j.biopha.2019.109168. Epub 2019 Jul 1.

DOI:10.1016/j.biopha.2019.109168
PMID:31334700
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7104808/
Abstract

Sites of infection and inflammation can be misleading in oncology PET/CT imaging because these areas commonly show F-FDG activity. Caution in the interpretation must be taken to avoid the misdiagnosis of malignancy. Utilization of both CT findings as well as patient history can help differentiate benign infectious and inflammatory processes from malignancy, although occasionally additional work-up may be required. This article discusses the mechanism of F-FDG uptake in infection and inflammation with illustrative examples.

摘要

感染和炎症部位在肿瘤 PET/CT 成像中可能具有误导性,因为这些区域通常显示 F-FDG 活性。在解释时必须小心谨慎,以免误诊为恶性肿瘤。尽管有时可能需要进一步检查,但利用 CT 发现和患者病史有助于将良性感染和炎症过程与恶性肿瘤区分开来。本文讨论了 F-FDG 在感染和炎症中的摄取机制,并提供了示例。

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