Usmani Sharjeel, Jain Anjali, Al Riyami Khulood, Almarzouqi Hajar, Jayakrishan Vipin Velangadi, Kheruka Subash, Al Sukati Rashid
Department of Radiology and Nuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Centre, Muscat, Oman.
Indian J Nucl Med. 2024 Nov-Dec;39(6):466-468. doi: 10.4103/ijnm.ijnm_92_24. Epub 2025 Mar 20.
False positive findings in F-fluorodeoxyglucose positron emission tomography-computed tomography (F-FDG PET/CT) scans can present challenges in the accurate diagnosis and staging of various conditions. We report a case of a 52-year-old male with known adenocarcinoma of the stomach who underwent total gastrectomy and chemotherapy and was referred for F-FDG PET/CT to rule out recurrence. F-FDG PET/CT showed a large FDG-avid lesion involving the entire right testicle mimicking testicular cancer or lymphoma. Further evaluation with ultrasonography revealed epididymo-orchitis, possibly of granulomatous etiology. Orchitis, an inflammatory condition of the testicles, can cause misleading results in F-FDG PET/CT imaging for cancer surveillance. Imagers should cautiously interpret PET/CT findings, considering clinical context, patient history, and additional imaging modalities to distinguish true malignancies from false positives.
18F-氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描（18F-FDG PET/CT）扫描中的假阳性结果可能给各种疾病的准确诊断和分期带来挑战。我们报告一例52岁男性病例，该患者已知患有胃腺癌，接受了全胃切除术和化疗，之后因排除复发而接受18F-FDG PET/CT检查。18F-FDG PET/CT显示一个累及整个右侧睾丸的FDG摄取增高的大病灶，类似睾丸癌或淋巴瘤。超声进一步检查显示附睾睾丸炎，可能为肉芽肿性病因。睾丸炎是睾丸的一种炎症性疾病，在用于癌症监测的18F-FDG PET/CT成像中可能导致误导性结果。影像科医生应谨慎解读PET/CT检查结果，考虑临床背景、患者病史和其他成像方式，以区分真正的恶性肿瘤和假阳性结果。
