Oppenheim Julius, Gray Mike H B, Di Bilio Angel J, Brennan Bradley J, Henling Lawrence M, Lim Punnajit, Soll Matan, Termini John, Virgil Scott C, Gross Zeev, Gray Harry B
Beckman Institute , California Institute of Technology , Pasadena , California 91125 , United States.
Department of Chemistry , Occidental College , Los Angeles , California 90041 , United States.
Inorg Chem. 2019 Aug 5;58(15):10287-10294. doi: 10.1021/acs.inorgchem.9b01441. Epub 2019 Jul 23.
In aqueous media, hydrophobic metallocorroles form nanoparticles that are potential theranostic anticancer agents. We have analyzed the electronic and Raman spectra of Al(III), Ga(III), and Au(III) corrole nanoparticles (and made comparisons with DFT-validated assignments of the IR spectra of corresponding monomers) in order to estimate the strengths of corrole-corrole electronic couplings in these assemblies. We find that these spectra are virtually unchanged upon aggregation, confirming that the intermolecular interactions in these nanoparticles are very weak.
在水性介质中，疏水性金属卟吩形成纳米颗粒，这些纳米颗粒是潜在的治疗诊断用抗癌剂。我们分析了铝（III）、镓（III）和金（III）卟吩纳米颗粒的电子光谱和拉曼光谱（并与相应单体红外光谱的密度泛函理论验证归属进行了比较），以估计这些组装体中卟吩 - 卟吩电子耦合的强度。我们发现，聚集后这些光谱几乎没有变化，这证实了这些纳米颗粒中的分子间相互作用非常弱。
