Liao Jianglong, Wang Tao, Dong Wei, Yang Jingfan, Zhang Jun, Li Lvyu, Chen Jiankun, Li Jian, Li Deguang, Ma Yunxi, Zhang Xiaoyan, Tang Xiaoxia, Jiang Bo, Guo Ying
Kunming Municipal Hospital of Traditional Chinese Medicine, Kunming, Yunnan, China.
Medicine (Baltimore). 2019 Jul;98(29):e16478. doi: 10.1097/MD.0000000000016478.
The aim of this study was to evaluate the effect of acupuncture injection therapy for the patients with nonspecific chronic low back pain (CLBP) systematically.
Four English online databases and 4 Chinese online databases will be researched systematically from their inception to December 31, 2018. Reference management software, Endnote X7, will be used to manage and screen the records. After removing the duplicate records, 2 independent reviewers will select the studies that meet the inclusion criteria. "Risk of table" recommend by Cochrane Handbook for Systematic Reviews of Interventions will be used to judge the quality of the included records. All data will be extracted by 1 reviewer and checked by another reviewer. Any disagree will be addressed via consulting a third reviewer in the above processes. Microsoft Excel will be used to manage and convert data if necessary. The missing data will be obtained via emailing the original authors of included studies. Review Manager (RevMan5.3) will be used to perform the data synthesis if enough data were collected. Otherwise, only the qualitative analysis will be performed. Based on the heterogeneity results, fixed-effect model or random-effect model will be used to estimate the overall effect of acupuncture injection therapy for patients with nonspecific CLBP. Meta-regression and subgroup analysis will be also performed to explore the sources of heterogeneity. If there are enough records included, the publish bias will be assessed by funnel plot. All procedures will be strictly performed in accordance with the Cochrane Handbook for Systematic Reviews of Interventions.
This review will offer clinical evidence of acupuncture injection therapy for the patients with nonspecific CLBP.
CRD42019119158.
本研究旨在系统评价针刺注射疗法对非特异性慢性下腰痛（CLBP）患者的疗效。
将对4个英文在线数据库和4个中文在线数据库从建库至2018年12月31日进行系统检索。使用文献管理软件Endnote X7来管理和筛选记录。去除重复记录后，由2名独立的审阅者选择符合纳入标准的研究。将采用Cochrane系统评价干预措施手册推荐的“偏倚风险”来判断纳入记录的质量。所有数据将由1名审阅者提取，并由另一名审阅者进行核对。在上述过程中，如有任何分歧将通过咨询第三名审阅者来解决。如有必要，将使用Microsoft Excel来管理和转换数据。缺失的数据将通过电子邮件联系纳入研究的原始作者获取。如果收集到足够的数据，将使用Review Manager（RevMan5.3）进行数据合成。否则，仅进行定性分析。根据异质性结果，将使用固定效应模型或随机效应模型来估计针刺注射疗法对非特异性CLBP患者的总体疗效。还将进行Meta回归和亚组分析以探索异质性来源。如果纳入了足够的记录，将通过漏斗图评估发表偏倚。所有程序将严格按照Cochrane系统评价干预措施手册进行。
本综述将为针刺注射疗法治疗非特异性CLBP患者提供临床证据。
PROSPERO研究注册号：CRD42019119158。
