Stock W, Geppert E, Zehle A
Thoraxchir Vask Chir. 1975 Aug;23(4):324-9. doi: 10.1055/s-0028-1096974.
The symptoms of the tourniquet syndrome (hypotonia, tachycardia, postischemic edema, hypercaliemia, metabolic acidosis, myoglobinuria, renal insufficiency) could be observed after embolectomy of saddle embolism in 37 patients. 19 patients died postoperatively; heart insufficiency was demonstrated by autopsy in 14 patients. The pathophysiology of heart failure in tourniquet syndrome was studied in dog experiments after unilateral and bilateral hind limb ischemia. The development of shock turned out to be more severe after bilateral ischemia--comparable to saddle embolism--than after unilateral ischemia. The course of heart failure after recirculation could be referred to hypercaliemia, hypermagnesiemia, metabolic acidosis and hemoconcentration. The prophylaxis of the tourniquet syndrome can be practised by knowing the pathogenesis.
在37例鞍状栓塞取栓术后可观察到止血带综合征的症状（肌张力减退、心动过速、缺血后水肿、高钙血症、代谢性酸中毒、肌红蛋白尿、肾功能不全）。19例患者术后死亡；尸检显示14例患者存在心力衰竭。通过单侧和双侧后肢缺血的犬实验研究了止血带综合征中心力衰竭的病理生理学。结果发现，双侧缺血后休克的发展比单侧缺血后更严重——与鞍状栓塞相当。再灌注后心力衰竭的病程可能与高钙血症、高镁血症、代谢性酸中毒和血液浓缩有关。了解发病机制可对止血带综合征进行预防。
